Results 71 to 80 of about 28,026 (256)

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

open access: yesSmall, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi   +13 more
wiley   +1 more source

Holling Type I versus Holling Type II functional responses in Gram-negative bacteria [PDF]

open access: yes, 2018
We consider how the double-membrane structure of the cell envelope of Gram-negative bacteria affects its functional response, which is the mathematical relationship that expresses how the nutrient uptake flux depends on environmental conditions.
Berg, Hugo van den, Nev, Olga
core   +2 more sources

Chromosome‐scale genome assembly of the South American fruit fly, Anastrepha fraterculus sp.1

open access: yesInsect Science, EarlyView.
Anastrepha fraterculus sp. 1 is a major fruit fly pest in Argentina, currently controlled through chemical treatments and traps. This study aims to enhance the genomic understanding of this species to support the development of sterile insect technique as well as the use of innovative technologies.
Máximo Rivarola   +15 more
wiley   +1 more source

The Role of the Hfq Protein in Bacterial Resistance to Antibiotics: A Narrative Review

open access: yesMicroorganisms
The antibiotic resistance of pathogenic microorganisms is currently one of most major medical problems, causing a few million deaths every year worldwide due to untreatable bacterial infections.
Sylwia Bloch   +2 more
doaj   +1 more source

Teleological cooption of Mycobacterium tuberculosis PE/PPE proteins as porins: Role in molecular immigration and emigration

open access: yesInternational Journal of Medical Microbiology, 2021
Permeation through bacterial cells for exchange or uptake of biomolecules and ions invariably depend upon the existence of pore-forming proteins (porins) in their outer membrane. Mycobacterium tuberculosis (M.
Aquib Ehtram   +8 more
doaj   +1 more source

Role of metal-dependent regulation of ESX-3 secretion in intracellular survival of Mycobacterium tuberculosis [PDF]

open access: yes, 2016
More people die every year from Mycobacterium tuberculosis infection than from infection by any other bacterial pathogen. Type VII secretion systems (T7SS) are used by both environmental and pathogenic mycobacteria to secrete proteins across their ...
Philips, Jennifer A   +5 more
core   +2 more sources

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

open access: yesThe FEBS Journal, EarlyView.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

The ribosome‐associated complex regulates cytosolic translation upon mitoprotein‐induced stress

open access: yesThe FEBS Journal, EarlyView.
Defects in mitochondrial protein import trigger a stress response. The contribution of translation regulation to such a response is only partially understood. We demonstrate that the deletion of mitochondrial surface proteins (TOM70/TOM71) leads to defects in mitochondrial biogenesis and slow growth.
Jiaxin Qian   +7 more
wiley   +1 more source

Fluoroquinolone Metalloantibiotics to Bypass Antimicrobial Resistance Mechanisms: Decreased Permeation through Porins

open access: yesMembranes, 2020
Fluoroquinolones (FQs) are broad-spectrum antibiotics largely used in the clinical practice against Gram-negative and some Gram-positive bacteria. Nevertheless, bacteria have developed several antimicrobial resistance mechanisms against such class of ...
Mariana Ferreira   +2 more
doaj   +1 more source

Silver resistance in Gram-negative bacteria: a dissection of endogenous and exogenous mechanisms [PDF]

open access: yes, 2015
Objectives: To gain a more detailed understanding of endogenous (mutational) and exogenous (horizontally acquired) resistance to silver in Gram-negative pathogens, with an emphasis on clarifying the genetic bases for resistance.
Busse, D   +4 more
core   +2 more sources

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