Results 21 to 30 of about 6,258,452 (248)

Role of SUMO-1 modification in transcriptional activation [PDF]

open access: yes, 2012
In unstimulated cells, the transcription factor NF-κB is held in the cytoplasm in an inactive state by IκB inhibitor proteins. Activation of NF--KB is mediated by signal induced degradation of IκBα via the ubiquitin proteasome-dependent pathway ...
Pinto Desterro, Maria Joana
core   +1 more source

Novel insights into the multifaceted roles of m6A-modified LncRNAs in cancers: biological functions and therapeutic applications

open access: yesBiomarker Research, 2023
N6-methyladenosine (m6A) is considered as the most common and important internal transcript modification in several diseases like type 2 diabetes, schizophrenia and especially cancer.
Jinxin Tang   +7 more
doaj   +1 more source

Post-transcriptional regulation in the developing embryo [PDF]

open access: yes, 2019
Embryonic development is critically reliant on well-defined spatial and temporal patterns of gene expression. These patterns are often achieved through the regulation of gene expression at the mRNA level.
Fernandes, Sara Maria Ferreira
core   +1 more source

Transcriptional gene silencing mutants in "Arabidopsis thaliana" and their impact on nuclear architecture and heterochromatin organization [PDF]

open access: yes, 2004
The epigenetic regulation of gene expression is defined by covalent modifications of DNA and histone tails as well as by chromatin structure and nuclear architecture.
Valeska Probst, Aline
core   +1 more source

Post-transcriptional features quantified in modeled genes.

open access: yes, 2016
Post-transcriptional features quantified in modeled genes.
Angela Re (3385214)   +2 more
core   +1 more source

Transcriptional and post-transcriptional regulation of ATP-binding cassette transporters.

open access: yes, 2004
Transcriptional and post-transcriptional regulation of ATP-binding cassette ...
Pui Lai Rachel. Ee (7996370)
core   +4 more sources

Transcriptional regulation mediated through the conjugation and deconjugation of the small ubiquitin-like modifiers SUMO-1, SUMO-2, and SUMO-3 [PDF]

open access: yes, 2012
SUMO-1/2/3 are members of the ubiquitin-like family of protein modifiers. These proteins are covalently attached to numerous proteins in a directed and controlled manner.
Girdwood, David William Haxton
core   +1 more source

Multilevel Regulation of Abiotic Stress Responses in Plants

open access: yesFrontiers in Plant Science, 2017
The sessile lifestyle of plants requires them to cope with stresses in situ. Plants overcome abiotic stresses by altering structure/morphology, and in some extreme conditions, by compressing the life cycle to survive the stresses in the form of seeds ...
David C. Haak   +6 more
doaj   +1 more source

Modeling cross‐talk of RNA modification enzymes reveals tumor microenvironment‐associated clinical significance and immunotherapy prediction in hepatobiliary malignancy

open access: yesMedComm, 2023
RNA modification includes four main types, N6‐methyladenosine, N1‐methyladenosine, alternative polyadenylation (APA), and adenosine‐to‐inosine (A‐to‐I) RNA editing, involving 41 enzymes that serve as “writers”, “readers” and “erasers”.
Feng Qi   +6 more
doaj   +1 more source

Combining tRNA sequencing methods to characterize plant tRNA expression and post-transcriptional modification

open access: yes, 2020
Differences in tRNA expression have been implicated in a remarkable number of biological processes. There is growing evidence that tRNA genes can play dramatically different roles depending on both expression and post-transcriptional modification, yet ...
Thalia Salinas-Giegé (8372601)   +7 more
core   +1 more source

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