Results 1 to 10 of about 76,713 (187)

Post-Translational Modifications (PTMs) of mutp53 and Epigenetic Changes Induced by mutp53 [PDF]

Biology
Wild-type (wt) p53 and mutant forms (mutp53) play a key but opposite role in carcinogenesis. wtP53 acts as an oncosuppressor, preventing oncogenic transformation, while mutp53, which loses this property, may instead favor this process. This suggests that
Rossella Benedetti, Michele Di Crosta, Gabriella D’Orazi, Mara Cirone   +3 more
doaj   +3 more sources

Editorial: Targeting Protein Post-Translational Modifications (PTMs) for Diagnosis and Treatment of Sepsis [PDF]

Frontiers in Immunology, 2022
Panpan Chang, Panpan Chang, Panpan Chang, Yongqing Li   +3 more
doaj   +4 more sources

Antioxidant systems are regulated by nitric oxide-mediated post-translational modifications (NO-PTMs) [PDF]

Frontiers in Plant Science, 2016
Nitric oxide (NO) is a biological messenger that orchestrates a plethora of plant functions, mainly through post-translational modifications (PTMs) such as S-nitrosylation or tyrosine nitration.
Juan Carlos Begara-Morales, Beatriz eSánchez-Calvo, Mounira eChaki, Raquel eValderrama, Capilla eMata-Pérez, Maria N Padilla, Francisco J Corpas, Juan B Barroso   +7 more
doaj   +4 more sources

Post-translational modifications and their implications in cancer [PDF]

Frontiers in Oncology, 2023
Post-translational modifications (PTMs) are crucial regulatory mechanisms that alter the properties of a protein by covalently attaching a modified chemical group to some of its amino acid residues. PTMs modulate essential physiological processes such as
Hashnu Dutta, Hashnu Dutta, Nishant Jain, Nishant Jain   +3 more
doaj   +3 more sources

Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation [PDF]

Frontiers in Neurology, 2021
Post-translational modifications (PTMs) on tau have long been recognized as affecting protein function and contributing to neurodegeneration. The explosion of information on potential and observed PTMs on tau provides an opportunity to better understand ...
Carolina Alquezar, Shruti Arya, Aimee W. Kao   +2 more
doaj   +3 more sources

Protein Modifications as Potential Biomarkers in Breast Cancer [PDF]

Biomarker Insights, 2009
A variety of post-translational protein modifications (PTMs) are known to be altered as a result of cancer development. Thus, these PTMs are potentially useful biomarkers for breast cancer. Mass spectrometry, antibody microarrays and immunohistochemistry
Hongjun Jin, Richard C. Zangar
doaj   +6 more sources

Role of Host-Mediated Post-Translational Modifications (PTMs) in RNA Virus Pathogenesis. [PDF]

Int J Mol Sci, 2020
Kumar R, Mehta D, Mishra N, Nayak D, Sunil S.   +4 more
europepmc   +3 more sources

Analysis of STAT3 post-translational modifications (PTMs) in human prostate cancer with different Gleason Score. [PDF]

Oncotarget, 2017
Cocchiola R, Romaniello D, Grillo C, Altieri F, Liberti M, Magliocca FM, Chichiarelli S, Marrocco I, Borgoni G, Perugia G, Eufemi M.   +10 more
europepmc   +3 more sources

Common Post-translational Modifications (PTMs) of Proteins: Analysis by Up-to-Date Analytical Techniques with an Emphasis on Barley. [PDF]

J Agric Food Chem, 2023
Bobalova J, Strouhalova D, Bobal P.
europepmc   +2 more sources

Towards a Universal Translator: Decoding the PTMs That Regulate Orthoflavivirus Infection [PDF]

Viruses
Post-translational modifications (PTMs) serve as critical regulators of protein function across biological systems, including during viral infection. For orthoflaviviruses, including human pathogens like dengue, Zika, and West Nile viruses, PTMs on viral
Hannah M. Schmidt, Stacy M. Horner
doaj   +2 more sources