Results 1 to 10 of about 41,962 (282)

Antioxidant Systems are Regulated by Nitric Oxide-Mediated Post-translational Modifications (NO-PTMs) [PDF]

Frontiers in Plant Science, 2016
Nitric oxide (NO) is a biological messenger that orchestrates a plethora of plant functions, mainly through post-translational modifications (PTMs) such as S-nitrosylation or tyrosine nitration.
Juan Carlos Begara-Morales, Beatriz Sánchez-Calvo, Mounira Chaki   +2 more
exaly   +6 more sources

Editorial: Targeting Protein Post-Translational Modifications (PTMs) for Diagnosis and Treatment of Sepsis [PDF]

Frontiers in Immunology, 2022
Panpan Chang, Panpan Chang, Panpan Chang, Yongqing Li   +3 more
doaj   +4 more sources

Novel Sarcopenia-related Alterations in Sarcomeric Protein Post-translational Modifications (PTMs) in Skeletal Muscles Identified by Top-down Proteomics [PDF]

Molecular and Cellular Proteomics, 2018
Zachery R Gregorich, Ziqing Lin, Wenxuan Cai   +2 more
exaly   +4 more sources

Post-Translational Modifications (PTMs) of mutp53 and Epigenetic Changes Induced by mutp53 [PDF]

Biology
Wild-type (wt) p53 and mutant forms (mutp53) play a key but opposite role in carcinogenesis. wtP53 acts as an oncosuppressor, preventing oncogenic transformation, while mutp53, which loses this property, may instead favor this process. This suggests that
Rossella Benedetti, Michele Di Crosta, Gabriella D’Orazi, Mara Cirone   +3 more
doaj   +2 more sources

Proteomic Analysis of Histone Variants and Their PTMs: Strategies and Pitfalls

Proteomes, 2018
Epigenetic modifications contribute to the determination of cell fate and differentiation. The molecular mechanisms underlying histone variants and post-translational modifications (PTMs) have been studied in the contexts of development, differentiation,
Sara El Kennani, Jerome Govin, Delphine Pflieger   +2 more
exaly   +3 more sources

Post-translational modifications and their implications in cancer

Frontiers in Oncology, 2023
Post-translational modifications (PTMs) are crucial regulatory mechanisms that alter the properties of a protein by covalently attaching a modified chemical group to some of its amino acid residues. PTMs modulate essential physiological processes such as
Hashnu Dutta, Hashnu Dutta, Nishant Jain, Nishant Jain   +3 more
doaj   +1 more source

Mass spectrometry-based direct detection of multiple types of protein thiol modifications in pancreatic beta cells under endoplasmic reticulum stress

Redox Biology, 2021
Thiol-based post-translational modifications (PTMs) play a key role in redox-dependent regulation and signaling. Functional cysteine (Cys) sites serve as redox switches, regulated through multiple types of PTMs.
Xiaolu Li, Nicholas J. Day, Song Feng, Matthew J. Gaffrey, Tai-Du Lin, Vanessa L. Paurus, Matthew E. Monroe, Ronald J. Moore, Bin Yang, Ming Xian, Wei-Jun Qian   +10 more
doaj   +1 more source

Special Issue “Structure, Activity, and Function of Protein Methyltransferases”

Life, 2022
Post-translational modifications (PTMs) largely expand the functional diversity of the proteome [...]
Arunkumar Dhayalan, Albert Jeltsch
doaj   +1 more source

PTMViz: a tool for analyzing and visualizing histone post translational modification data

BMC Bioinformatics, 2021
Background Histone post-translational modifications (PTMs) play an important role in our system by regulating the structure of chromatin and therefore contribute to the regulation of gene and protein expression. Irregularities in histone PTMs can lead to
Kevin Chappell, Stefan Graw, Charity L. Washam, Aaron J. Storey, Chris Bolden, Eric C. Peterson, Stephanie D. Byrum   +6 more
doaj   +1 more source

Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation

Frontiers in Neurology, 2021
Post-translational modifications (PTMs) on tau have long been recognized as affecting protein function and contributing to neurodegeneration. The explosion of information on potential and observed PTMs on tau provides an opportunity to better understand ...
Carolina Alquezar, Shruti Arya, Aimee W. Kao   +2 more
doaj   +1 more source