Beyond phosphorylation:Putative roles of post-translational modifications in plasmodium sexual stages [PDF]
, 2021 Post-translational modifications (PTMs) allow proteins to regulate their structure, localisation and function in response to cell intrinsic and environmental signals.
Johnson, Nila, Philip, Nisha
core +1 more source
, 2022 <p>A procedure to identify single amino acids (AAs) in the bulk or with a few molecules from a single binary measurement is introduced. Combined with Edman degradation (or other method) it can be used to sequence a peptide or identify the parent protein from a partial sequence.
G Sampath
+5 more sources
Cas9 Protein Post-translational Modifications (PTMs): A Potential Biomarker of Gene-editing
, 2019 Joshua D. Podlevsky
openalex +3 more sources
Special Issue “Structure, Activity, and Function of Protein Methyltransferases”
Life, 2022 Post-translational modifications (PTMs) largely expand the functional diversity of the proteome [...]
Arunkumar Dhayalan, Albert Jeltsch
doaj +1 more source
Post-Translational Modifications and Age-Related Hearing Loss [PDF]
, 2022 Post-translational modifications (PTMs) affect nearly all systems of the human body due to their role in protein synthesis and functionality. These reversible and irreversible modifications control the structure, localization, activity, and properties of
Acosta, Alejandro A. +10 more
core +2 more sources
PTMViz: a tool for analyzing and visualizing histone post translational modification data
BMC Bioinformatics, 2021 Background Histone post-translational modifications (PTMs) play an important role in our system by regulating the structure of chromatin and therefore contribute to the regulation of gene and protein expression. Irregularities in histone PTMs can lead to
Kevin Chappell +6 more
doaj +1 more source
Coenzyme A levels influence protein acetylation, CoAlation and 4'-phosphopantetheinylation:Expanding the impact of a metabolic nexus molecule [PDF]
, 2021 Coenzyme A (CoA) is a key molecule in cellular metabolism including the tricarboxylic acid cycle, fatty acid synthesis, amino acid synthesis and lipid metabolism.
Grzeschik, Nicola A +4 more
core +1 more source
Human Proteomic Variation Revealed by Combining RNA-Seq Proteogenomics and Global Post-Translational Modification (G-PTM) Search Strategy [PDF]
Journal of Proteome Research, 2015 Mass-spectrometry-based proteomic analysis underestimates proteomic variation due to the absence of variant peptides and posttranslational modifications (PTMs) from standard protein databases. Each individual carries thousands of missense mutations that lead to single amino acid variants, but these are missed because they are absent from generic ...
Anthony J. Cesnik +4 more
openalex +4 more sources
RECENT ADVANCES IN POST-TRANSLATIONAL REGULATION OF PLANT DEFENSE RESPONSES BEYOND PHOSPHORYLATION [PDF]
Journal of Plant Development, 2021 During plant-microbe interactions, plant immune signaling relies significantly on post-translational modifications (PTMs) to induce rapid downstream changes.
Tim XING, Ziwei GUO
doaj +1 more source
Post-Translational Modifications in Atopic Dermatitis: Current Research and Clinical Relevance
Frontiers in Cell and Developmental Biology, 2022 Atopic dermatitis (AD) is a chronic and relapsing cutaneous disorder characterized by compromised immune system, excessive inflammation, and skin barrier disruption.
Xin Ma +17 more
doaj +1 more source