Results 41 to 50 of about 85,477 (330)

Stage-specific histone modification profiles reveal global transitions in the Xenopus embryonic epigenome. [PDF]

open access: yes, 2011
Vertebrate embryos are derived from a transitory pool of pluripotent cells. By the process of embryonic induction, these precursor cells are assigned to specific fates and differentiation programs.
Arteaga-Salas, Jose M.   +6 more
core   +10 more sources

Post-Translational Modifications in Atopic Dermatitis: Current Research and Clinical Relevance

open access: yesFrontiers in Cell and Developmental Biology, 2022
Atopic dermatitis (AD) is a chronic and relapsing cutaneous disorder characterized by compromised immune system, excessive inflammation, and skin barrier disruption.
Xin Ma   +17 more
doaj   +1 more source

Post‐translational modifications of histones: Mechanisms, biological functions, and therapeutic targets

open access: yesMedComm, 2023
Histones are DNA‐binding basic proteins found in chromosomes. After the histone translation, its amino tail undergoes various modifications, such as methylation, acetylation, phosphorylation, ubiquitination, malonylation, propionylation, butyrylation ...
Ruiqi Liu   +9 more
semanticscholar   +1 more source

Tubulin Post-Translational Modifications: The Elusive Roles of Acetylation

open access: yesBiology, 2023
Simple Summary Microtubules (MTs) are dynamic structures that compose part of the cell cytoskeleton. They play important roles in various cellular functions, such as intracellular transport, cell division, and cell movement.
Bruno Carmona   +4 more
semanticscholar   +1 more source

Investigation of post-translational modifications in type 2 diabetes

open access: yesClinical Proteomics, 2018
The investigation of post-translational modifications (PTMs) plays an important role for the study of type 2 diabetes. The importance of PTMs has been realized with the advancement of analytical techniques.
Bhaswati Chatterjee, Suman S. Thakur
doaj   +1 more source

Advances on Post-translational Modifications Involved in Seed Germination

open access: yesFrontiers in Plant Science, 2021
Seed germination and subsequent seedling establishment are important developmental processes that undergo extremely complex changes of physiological status and are precisely regulated at transcriptional and translational levels.
Feng Yu   +3 more
doaj   +1 more source

Development and optimization of a miniaturized western blot-based screening platform to identify regulators of post-translational modifications [PDF]

open access: yes, 2019
Post-translational modifications (PTMs) are fundamental traits of protein functionality and their study has been addressed using several approaches over the past years.
Gottifredi, Vanesa   +2 more
core   +1 more source

Roles of protein post-translational modifications in glucose and lipid metabolism: mechanisms and perspectives

open access: yesMolecular Medicine, 2023
The metabolism of glucose and lipids is essential for energy production in the body, and dysregulation of the metabolic pathways of these molecules is implicated in various acute and chronic diseases, such as type 2 diabetes, Alzheimer’s disease ...
Yu-Hang Yang   +4 more
semanticscholar   +1 more source

Deep Learning-Assisted Single-Molecule Detection of Protein Post-translational Modifications with a Biological Nanopore

open access: yesbioRxiv, 2023
Protein post-translational modifications (PTMs) play a crucial role in countless biological processes, profoundly modulating protein properties on both the spatial and temporal scales.
Chan Cao   +8 more
semanticscholar   +1 more source

An update on transcriptional and post-translational regulation of brain voltage-gated sodium channels [PDF]

open access: yes, 2015
Voltage-gated sodium channels are essential proteins in brain physiology, as they generate the sodium currents that initiate neuronal action potentials.
Beltran-Alvarez, Pedro   +1 more
core   +1 more source

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