Results 1 to 10 of about 132,714 (244)

Postsynaptic Potential Energy as Determinant of Synaptic Plasticity [PDF]

open access: yesFrontiers in Computational Neuroscience, 2022
Metabolic energy can be used as a unifying principle to control neuronal activity. However, whether and how metabolic energy alone can determine the outcome of synaptic plasticity remains unclear.
Huanwen Chen   +3 more
doaj   +6 more sources

Auditory Stimuli Coding by Postsynaptic Potential and Local Field Potential Features. [PDF]

open access: yesPLoS ONE, 2016
The relation between physical stimuli and neurophysiological responses, such as action potentials (spikes) and Local Field Potentials (LFP), has recently been experimented in order to explain how neurons encode auditory information.
Juliana M de Assis   +2 more
doaj   +2 more sources

Imperfect space clamp permits electrotonic interactions between inhibitory and excitatory synaptic conductances, distorting voltage clamp recordings. [PDF]

open access: yesPLoS ONE, 2011
The voltage clamp technique is frequently used to examine the strength and composition of synaptic input to neurons. Even accounting for imperfect voltage control of the entire cell membrane ("space clamp"), it is often assumed that currents measured at ...
Alon Poleg-Polsky, Jeffrey S Diamond
doaj   +1 more source

Pre & postsynaptic tuning of action potential timing by spontaneous GABAergic activity. [PDF]

open access: yesPLoS ONE, 2011
Frequency and timing of action potential discharge are key elements for coding and transfer of information between neurons. The nature and location of the synaptic contacts, the biophysical parameters of the receptor-operated channels and their kinetics ...
Olivier Caillard
doaj   +1 more source

Postsynaptic neuronal activity promotes regeneration of retinal axons

open access: yesCell Reports, 2023
Summary: The wiring of visual circuits requires that retinal neurons functionally connect to specific brain targets, a process that involves activity-dependent signaling between retinal axons and their postsynaptic targets.
Supraja G. Varadarajan   +5 more
doaj   +1 more source

Distribution of densin in neurons. [PDF]

open access: yesPLoS ONE, 2018
Densin is a scaffold protein known to associate with key elements of neuronal signaling. The present study examines the distribution of densin at the ultrastructural level in order to reveal potential sites that can support specific interactions of ...
Ayse Dosemeci   +3 more
doaj   +1 more source

Transcranial focused ultrasound induces sustained synaptic plasticity in rat hippocampus

open access: yesBrain Stimulation, 2022
Transcranial focused ultrasound (tFUS) neuromodulation provides a promising emerging non-invasive therapy for the treatment of neurological disorders.
Xiaodan Niu, Kai Yu, Bin He
doaj   +1 more source

AMPA Receptor Trafficking for Postsynaptic Potentiation [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2018
Long-term potentiation (LTP) of excitatory synaptic strength, which has long been considered a synaptic correlate for learning and memory, requires a fast recruitment of additional α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors (AMPARs) to the postsynaptic sites.
Mikyoung Park, Mikyoung Park
openaire   +3 more sources

Functional maps of neocortical local circuitry

open access: yesFrontiers in Neuroscience, 2007
This review aims to summarize data obtained with different techniques to provide a functional map of the local circuit connections made by neocortical neurones, a reference for those interested in cortical circuitry and the numerical information required
Alex M Thomson, Christophe Lamy
doaj   +1 more source

Influence of Mpv17 on Hair-Cell Mitochondrial Homeostasis, Synapse Integrity, and Vulnerability to Damage in the Zebrafish Lateral Line

open access: yesFrontiers in Cellular Neuroscience, 2021
Noise exposure is particularly stressful to hair-cell mitochondria, which must produce enough energy to meet high metabolic demands as well as regulate local intracellular Ca2+ concentrations.
Melanie Holmgren   +2 more
doaj   +1 more source

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