Acute application of Centella asiatica extract enhanced AMPAR-mediated postsynaptic currents in rat entorhinal cortex [PDF]
Centella asiatica is notable for its wide range of biological activities beneficial to human health, particularly its cognitive enhancement and neuroprotective effects.
Jia Hui Wong, Faruque Reza, Sangu Muthuraju, Huei Gau Chuang, Jingli Zhang, Mohd Harizal Senik, Siti Rafidah Yusof, Habsah Mohamad, Tengku Sifzizul Tengku Muhammad, Nor Hadiani Ismail, Jafri Malin Abdullah
doaj +1 more source
Data compression of excitatory postsynaptic potentials
Reducing the size of biosignal data is important because a huge amount of data is made by various experiments. In this reported work excitatory postsynaptic potentials (EPSPs) which are one of the biosignal types are efficiently compressed. To the best of authors’ knowledge, EPSPs compression has not been studied yet. The EPSP signal has a feature that
Hyejin An+3 more
openaire +2 more sources
ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib+16 more
wiley +1 more source
Spike-timing dependent plasticity in inhibitory circuits
Inhibitory circuits in the brain rely on GABA-releasing interneurons. For long, inhibitory circuits were considered weakly plastic in the face of patterns of neuronal activity that trigger long-term changes in the synapses between excitatory principal ...
Karri P Lamsa+2 more
doaj +1 more source
Effects of methylphenidate on the inhibitory postsynaptic potential in rat locus coeruleus neurons.
Effects of methylphenidate (MPH), an agent used clinically for the treatment of children presenting the attention-deficit/hyperactivity disorder (AD/HD), on synaptic transmission in the rat locus coeruleus (LC) were examined by intracellular recording ...
Takashi Kuwahata+3 more
semanticscholar +1 more source
Estimating the interaction graph of stochastic neural dynamics [PDF]
In this paper we address the question of statistical model selection for a class of stochastic models of biological neural nets. Models in this class are systems of interacting chains with memory of variable length. Each chain describes the activity of a single neuron, indicating whether it spikes or not at a given time.
arxiv +1 more source
Tunable Tactile Synapses Enabled by Erasable Doping in Iongel‐Gated Nanotube Network Transistors
Artificial tactile synaptic sensors are realized by an iongel‐gated single‐walled carbon nanotube (SWCNT) transistor with reversible doping characteristics. The device senses and memorizes tactile stimuli and exhibits gate bias‐dependent excitatory or inhibitory synaptic behavior.
Yan Huang+5 more
wiley +1 more source
Temperature‐Resilient Polymeric Memristors for Effective Deblurring in Static and Dynamic Imaging
A thermally stable organic memristor based on a thiadiazolobenzotriazole (TBZ) and 2,5‐Dioctyl‐3,6‐di(thiophen‐2‐yl)pyrrolo[3,4‐c]pyrrole‐1,4(2H,5H)‐dione (DPP)‐based conjugated polymer is presented, demonstrating reliable, gradual resistance switching across a wide temperature range (153–573 K).
Ziyu Lv+15 more
wiley +1 more source
A population of neurons interconnected by synapses constitutes a neural circuit, which performs specific functions upon activation. It is essential to identify both anatomical and functional entities of neural circuits to comprehend the components and ...
Allison N Castaneda+6 more
doaj +1 more source
Postsynaptic Target Specificity of Neurotrophin-Induced Presynaptic Potentiation [PDF]
The role of the target cell in neurotrophin-induced modifications of glutamatergic synaptic transmission was examined in cultured hippocampal neurons. Brain-derived neurotrophic factor (BDNF) induced rapid and persistent potentiation of evoked glutamate release when the postsynaptic neuron was glutamatergic, or excitatory (E-->E), but not when it was ...
Benedikt Berninger+2 more
openaire +3 more sources