Results 101 to 110 of about 1,524,654 (239)

KATP channels in cerebral hemodynamics: a systematic review of preclinical and clinical studies

Frontiers in Neurology
Cumulative evidence suggests that ATP-sensitive potassium (KATP) channels act as a key regulator of cerebral blood flow (CBF). This implication seems to be complicated, since KATP channels are expressed in several vascular-related structures such as ...
Hassan Ali Suleiman Daoud, Lili Kokoti, Mohammad Al-Mahdi Al-Karagholi, Mohammad Al-Mahdi Al-Karagholi, Mohammad Al-Mahdi Al-Karagholi   +4 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Cromakalim, a Potassium Channel Opener, Ameliorates the Organophosphate and Carbamate-Induced Seizure in Mice

Acta Medica Iranica, 2018
Organophosphates (OPs) and carbamates are acetylcholine esterase inhibitors (AChEIs), which can cause seizure and lethality. Anticonvulsant properties of potassium channel openers including cromakalim have been determined in previous studies.
Sattar Ostadhadi, Abouzar Moradi, Samira Zolfaghari, Vahid Nikoui, Ahmad Reza Dehpour   +4 more
doaj  

Inductively Expandable Supraparticles as Microscopic Force Generators for Remote Mechanical Actuation

Advanced Materials, EarlyView.
This study demonstrates the combination of magnetic nanoparticles and functional blowing agents into supraparticles. Upon induction heating, they actuate via rapid gas generation or extensive volume expansion. These supraparticles lift up to 25 000 times their own mass and rapidly open cured epoxy resins, providing a versatile strategy for fast micron ...
Leoni Luthardt, Stephan Müssig, Robert Luxenhofer, Karl Mandel   +3 more
wiley   +1 more source

Mitochondrial potassium and chloride channels. [PDF]

, 2000
Channels selective for potassium or chloride ions are present in inner mitochondrial membranes. They probably play an important role in mitochondrial events such as the formation of ΔpH and regulation of mitochondrial volume changes.
Kicińska, Anna, Szewczyk, Adam, Kunz, Wolfram, Dębska, Grażyna   +3 more
core  

Dynamic Electrophoretic Assembly Coupled With Water‐Splitting‐Induced pH Control Enables Precision Ion Sieving Membranes

Advanced Materials, EarlyView.
A green, external‐catalyst‐free route grows defect‐free covalent organic framework membranes directly on ion‐exchange supports using an alternating electric field and in situ‐generated acid. Through a self‐regulating, self‐healing mechanism, the membranes achieve near‐complete, ultra‐fast separation of monovalent ions such as Li+, Na+, and K+, offering
Mohammad Hossein Jandaghian, Petric Marc Ruya, Ipek Ozyurt, Ali Atyabi, Samuel Eyley, Wim Thielemans, Alexander Volodin, Riccardo Alessandri, Xing Yang   +8 more
wiley   +1 more source

Potassium Channel Openers Exhibit Cross-tolerance with Morphine in Two Experimental Models of Pain

, 2011
Objective: The study was performed to assess the effect of potassium channel openers on morphine tolerance and vice-versa. Methods: Swiss albino mice of either gender weighing between 25−30 g were used for the study.
. N Khanna, RS Malhotra, AK Mehta, GR Garg, S Halder, KK Sharma
core  

Effect of potassium channel modulators on the release of glutamate induced by ischaemic-like conditions in rat hippocampal slices.

, 1993
The effects of the potassium channel openers lemakalim, RP 52891 and galanin and the potassium channel blockers glibenclamide and gliquidone were evaluated by the release of endogenous glutamate from rat hippocampal slices subjected to a brief period of ...
Zini, S., Roisin, M. P., Ben-Ari, Y., Armengaud, Catherine, Armengaud, C.   +4 more
core   +1 more source

Ionic Gating of Liquid‐Crystal‐Like Pteridine Assemblies Enables Tunable Light Scattering

Advanced Materials, EarlyView.
Tunable optical properties emerge through developmentally regulated ionic gating, which transforms disordered, ultraviolet (UV)‐absorbing organelles into concentrically ordered, liquid‐crystal‐like light scatterers. By integrating analyses of pteridine composition, potassium‐dependent assembly, hierarchical ultrastructure, and optical behavior, the ...
Sourabh Bera, Zohar Eyal, Yael Noy, Yuval Barzilay, Siddharth Sahoo, Srikant Moharana, Avi Baram, Tali Lerer‐Goldshtein, Neta Varsano, Bar Bader, Lothar Houben, Uwe Heinig, Iddo Pinkas, Moshe Goldsmith, Tamar Unger, Shira Albeck, Andrea Sorrentino, Maxim Itkin, Sergey Malitsky, Ziv Porat, Ido Hadar, Venkata Jayasurya Yallapragada, Dvir Gur   +22 more
wiley   +1 more source

Epitaxially Integrated Electro‐Optic KNbO3 Thin Films on Silicon

Advanced Materials, EarlyView.
We demonstrate the first epitaxial integration of electro‐optic KNbO3 thin films on silicon using suboxide molecular‐beam epitaxy. Combining adsorption‐controlled molecular‐beam epitaxy, advanced characterization, and phase‐field modeling, we demonstrate phase‐pure crystalline films mirroring bulk crystals with robust Pockels response, enabling future ...
Sankalpa Hazra, Tobias Schwaigert, Yingxin Zhu, Aiden Ross, Muhammad Aminul Haque Chowdhury, Shun‐Li Shang, Sameer Singh, Zhiyu Zhang, Zhe Wang, Brynn Brower, Saugata Sarker, Suchismita Sarker, Zi‐Kui Liu, Rama K. Vasudevan, Long‐Qing Chen, Yang Yang, Darrell G. Schlom, Venkatraman Gopalan   +17 more
wiley   +1 more source