Results 111 to 120 of about 5,395 (299)

Modulation of Mitochondrial Bioenergetics in the Isolated Guinea Pig Beating Heart by Potassium and Lidocaine Cardioplegia: Implications for Cardioprotection [PDF]

, 2009
Mitochondria are damaged by cardiac ischemia/reperfusion (I/R) injury but can contribute to cardioprotection. We tested if hyperkalemic cardioplegia (CP) and lidocaine (LID) differently modulate mitochondrial (m) bioenergetics and protect hearts against ...
Aldakkak, Mohammed, Camara, Amadou K.S., Chen, Qun, Heisner, James S., Lesnefsky, Edward J., Stowe, David F.   +5 more
core   +2 more sources

Robust Polymer Hydrogels Improve Electric‐Fish‐Inspired Batteries

Advanced Functional Materials, EarlyView.
ABSTRACT Electric‐fish‐inspired hydrogel batteries based on ion‐concentration gradients offer an attractive route to soft power sources; however, the poor mechanical properties of existing hydrogels limit device assembly and performance. Here, we report poly(ethylene glycol) methyl ether acrylate hydrogels that enable ion‐gradient batteries composed of
Nick Zahnd, Satyajit Das, John Marc C. Puguan, Carolina Pierucci, Michael Mayer, Christoph Weder   +5 more
wiley   +1 more source

Toward Stable Multivalent Metal Batteries: Understanding the Interfacial Chemistry for Magnesium and Calcium Metal Anodes

Advanced Functional Materials, EarlyView.
Interphase chemistry governs the stability of multivalent metal batteries. We summarize state‐of‐the‐art developments in calcium and magnesium metal batteries by focusing on the correlation among electrolytes, interphase layers, and the electrochemical performance of corresponding metal anodes.
Huijun Lin, Qi Meng, Juncai Long, Chuheng Cao, Zheng‐Long Xu   +4 more
wiley   +1 more source

Experimental pharmacological approaches to reverse impaired awareness of hypoglycemia—a review

Frontiers in Pharmacology
The colossal global burden of diabetes management is compounded by the serious complication of hypoglycemia. Protective physiologic hormonal and neurogenic counterregulatory responses to hypoglycemia are essential to preserve glucose homeostasis and ...
Hiba Z. Hashmi, Ameer Khowaja, Amir Moheet   +2 more
doaj   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

Advanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim, Uijung Yong, Myungji Kim, Jaewook Kim, Yeonggwon Jo, In Kyong Shim, Song Cheol Kim, Jinah Jang   +7 more
wiley   +1 more source

M‐type K⁺ channels in peripheral nociceptive pathways

, 2018
Pathological pain is a hyperexcitability disorder. Since the excitability of a neuron is set and controlled by a complement of ion channels it expresses, in order to understand and treat pain, we need to develop a mechanistic insight into the key ion ...
Abd-Elsayed, Alexander, Alexander, Alexander, Alexander, Amir, Anonymous, Bandell, Barkai, Bentzen, Bernal, Bierbower, Breivik, Breyer, Brown, Brueggemann, Bushell, Cai, Campbell, Chen, Cisneros, Couture, Crozier, Cruzblanca, Dalby-Brown, Daniluk, Davoren, Debanne, Delmas, Devaux, Devor, Devor, Devulder, Dray, Du, Du, Fawcett, Ferrero-Miliani, Filippov, Fritch, Gamper, Gamper, Gamper, Gamper, Gao, Gao, Gemes, Govrin-Lippmann, Greene, Gribkoff, Grunnet, Ha, Hayashi, Heidenreich, Hernandez, Hille, Hirano, Hoheisel, Hoshi, Huang, Huang, Huang, Iannotti, Jentsch, Jia, Jin, Kanda, Keele, King, King, Kolosov, Kosenko, Kuhn, Kumar, L'Heureux, Lang, Laumet, Lee, Li, Linley, Linley, Linley, Linley, Liu, Liu, Luscher, Miceli, Mucha, Munro, O'Connor, Ooi, Ooi, Passmore, Passmore, Peiris, Peretz, Peretz, Peretz, Petho, Prinsloo, Qi, Rivera-Arconada, Rivera-Arconada, Rose, Roza, Roza, Schenzer, Schroeder, Schutze, Serhan, Shapiro, Southan, Stafstrom, Stoney, Stott, Sugiura, Suh, Suh, Sundt, Tatulian, Tatulian, Teng, Uchida, Vetter, Visockis, Wall, Wang, Wang, Wickenden, Wickenden, Willis, Wladyka, Wood, Wu, Wu, Wu, Wu, Wuttke, Xiong, Xu, Zaika, Zaika, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zheng   +148 more
core   +1 more source

The Terminal Domains of Collagen‐Like Silk Direct Molecular Interactions and Liquid–Liquid Phase Separation‐Mediated Material Assembly

Advanced Functional Materials, EarlyView.
Terminal domains of recombinant collagen‐like silk regulate hierarchical self‐assembly across molecular and material scales. We show that terminal domains of collagen‐like silk enhance triple‐helix stability and drive liquid–liquid phase separation, enabling reversible formation of fibers and self‐healing films.
Mengjie Shen, Daniil Astapov, Nur Alia Oktaviani, Mami Goto, Keiji Numata, A. Sesilja Aranko   +5 more
wiley   +1 more source

MXene/PEDOT Functional Coatings on Flexible Microelectrode Arrays for Multianalyte In Vivo Neurochemical Sensing and Electrophysiology

Advanced Functional Materials, EarlyView.
A MXene/PEDOT coating enables multimodal functionality and dual‐analyte detection of dopamine and serotonin in flexible microelectrode arrays while enhancing electrophysiological recording quality. The anti‐fouling, low‐impedance interface overcomes key limitations of conventional coatings, providing a robust and versatile platform to investigate the ...
Ilaria Gatti, Karamullah Eisawi, Umisha Siwakoti, Greyson Jadwin, Ashmita Sigdel, Michela Chiappalone, Deepak Kumbhare, Michael Naguib, Elisa Castagnola   +8 more
wiley   +1 more source

Solvent Co‐Intercalation Enabled Ca Storage in MoS2 for Ca‐Ion Batteries

Advanced Functional Materials, EarlyView.
Regulating electrolyte solvation levels enables otherwise non‐intercalatable Ca2+ ions to reversibly co‐intercalate into molybdenum disulfide (MoS2) as ether‐solvated species. The intercalation reversibility is strongly governed by solvent chain length, as demonstrated using diethylene glycol dimethyl ether (G2) and tetraethylene glycol dimethyl ether (
Yudong Luo, Matthias Golomb, Yupei Han, Pan He, Neubi Xavier, Wanjun Ren, Yi Lu, Matthew Hopper, Henry R. Tinker, Qiong Cai, Yang Xu   +10 more
wiley   +1 more source

Erratum

Clinical Pharmacology: Advances and Applications, 2012
Barrese V, Miceli F, Soldovieri MV, Ambrosino P, Iannotti FA, Cilio MR, Taglialatela M. Neuronal potassium channel openers in the management of epilepsy: role and potential of retigabine. Clinical Pharmacology: Advances and Applications.
Barrese V, Miceli F, Soldovieri MV, Ambrosino P, Iannotti FA, Cilio MR, Taglialatela M   +6 more
doaj