Abstract Background Pregabalin reduces excitatory neurotransmitter release and is used for anxiolysis in humans, cats, and horses. The effects of pregabalin on equine recovery following isoflurane anaesthesia are unknown. Objectives To determine if pre‐anaesthetic oral pregabalin influences recovery time and/or quality from isoflurane anaesthesia in ...
Abigail Blanton +8 more
wiley +1 more source
Palmitic acid reduces cytosolic potassium and induces IL-1β production in lipopolysaccharide-primed human macrophages. [PDF]
Chuang JW, Lu SC.
europepmc +1 more source
A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer
Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge +3 more
wiley +1 more source
Photoelectrical control of apoptosis and autophagy. [PDF]
Mohammadiaria M.
europepmc +1 more source
Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito +8 more
wiley +1 more source
Crosstalk of KCNH1 and KCNH5 gain-of-function mutations leading to epilepsy and neurodevelopmental disorders. [PDF]
Bernert A +3 more
europepmc +1 more source
Evaluation of the performance of ChatGPT‐4 and ChatGPT‐4o as a learning tool in endodontics
Abstract Aims The aim of this study was to evaluate the accuracy and consistency of responses given by two different versions of Chat Generative Pre‐trained Transformer (ChatGPT), ChatGPT‐4, and ChatGPT‐4o, to multiple‐choice questions prepared from undergraduate endodontic education topics at different times of the day and on different days ...
Esra Arılı Öztürk +2 more
wiley +1 more source
Inhibition of cancerous properties of triple-negative MDA-MB-436 cells by targeting the K+ voltage-dependent Kv2.1 channel. [PDF]
Canella R +8 more
europepmc +1 more source
Unravelling the Genetic Mechanisms of Litter Traits in a Maternal Line of Pigs
ABSTRACT Reproductive traits related to litter size are the main indicators of reproductive efficiency in pig production and are continuously evaluated for the selection of maternal lines. Several environmental and genetic factors are involved with the development of these traits.
Guilherme Oselame +10 more
wiley +1 more source
Single-Neuron Critical Intermittency in a Stochastic Hodgkin-Huxley Model. [PDF]
Varvaras K, Diakonos FK, Kosmidis EK.
europepmc +1 more source

