Results 201 to 210 of about 1,936,204 (283)

Forward genetics reveals a conserved CNBHD-CNBHD interface that restrains EAG channel activation to regulate sleep. [PDF]

PLoS Genet
Huang X, Kannan S, Robertson GA, Wang H.
europepmc   +1 more source

ON/OFF Phenomenon in 4‐Aminopyridine Therapy in Spinocerebellar Ataxia 27B: Therapeutic and Diagnostic Insights

Movement Disorders Clinical Practice, EarlyView.
Chiara Caneda, Eleonora Bertoncello, Alessia Peghin, Sara Satolli, Filippo Maria Santorelli, Michele Tinazzi, Ilaria Antonella Di Vico   +6 more
wiley   +1 more source

Bioelectronic Wearable Sensors Produced by Computerized Embroidery Using a Dual Thread Approach

Small, EarlyView.
A dual‐thread embroidered SmartBra integrates silver‐plated and conductive‐polymer (PECOTEX) threads to enable simultaneous cardiac monitoring and open‐circuit potentiometric sensing of potassium and sodium in a breast milk substitute. The wearable platform is fabricated using computerized embroidery, offering a scalable, proof‐of‐concept route toward ...
Taliya Weinstein, Xintong Li, Hasan Kurt, Selin Olenik, Alexander Silva‐Pinto Collins, José Manuel Rodrigueiro Flauzino, Muhammed Adeel, Laura Gonzalez‐Macia, Meral Yüce, Firat Güder   +9 more
wiley   +1 more source

Channel Dysfunction as the Basis for Comorbidities in Multiple Sclerosis and Depression. [PDF]

Arch Pharm (Weinheim)
Rychlik N, Jüngling K, Meuth SG, Budde T, Méndez-Couz M.   +4 more
europepmc   +1 more source

A Cytoplasmic pH Sensor Redefines Gating in Bacterial Urea Channels and Acid Resistance

Small, EarlyView.
Bacterial survival in acidic environments requires pH‐gated urea channels. Utilizing complementary approaches, we identify a conserved cytoplasmic glutamic acid residue as a pH sensor in UreI channels. Whereas Gram‐positive bacteria rely solely on this sensor, Gram‐negative bacteria employ a dual‐sensor mechanism with periplasmic residues, revealing a ...
Anna Stoib, Sahar Shojaei, Xenia Fischer, Sandra Posch, Gianluca Parisse, Mario Frezzini, Tobias Putz, Christine Siligan, Nikolaus Goessweiner‐Mohr, Daniele Narzi, Andreas Horner   +10 more
wiley   +1 more source

The cornea-trigeminal axis: potassium channels as master regulators of ocular surface homeostasis and sensory transduction. [PDF]

Front Cell Dev Biol
Zhang J, Chen X, Ji J, Chen P, Yao J, Liu L, Tang L, Wen X.   +7 more
europepmc   +1 more source

Accessing Both Electrochemical SEIRA and SERS With Highly Sensitive Metamaterials for Enhanced Molecular Identification

Small, EarlyView.
Surface‐enhanced infrared absorption (SEIRA) and Raman scattering (SERS) are complementary, highly sensitive molecular detection methods. A reusable metamaterial substrate capable of combined SEIRA and SERS is used here for real‐time sensing, tracking interfacial dynamics in an electrochemical reaction and detecting symmetry‐breaking behavior at the ...
Nicolas Spiesshofer, Tabitha Jones, Sarah May Sibug‐Torres, Zoltan Sztranyovszky, Caleb Todd, Shijie Zhu, Yeeun Roh, Rakesh Arul, Alexander Squires, Ivana Qianqi Lin, Angela Demetriadou, David O. Scanlon, Viv Lindo, Jeremy J. Baumberg   +13 more
wiley   +1 more source

A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels. [PDF]

Ann Clin Transl Neurol
Ortigoza-Escobar JD, Marti-Sánchez L, Martorell L, Dinoi G, Buono AV, De Luca A, Liantonio A, Imbrici P.   +7 more
europepmc   +1 more source

Boron‐embedded multifunctional nanoplatform toward potential combined boron neutron capture therapy and immunomodulation in glioma

Smart Molecules, EarlyView.
A brain‐targeting multifunctional nanoplatform (DM&Ce6@COF‐Ang) was engineered by employing boron‐enriched APTES‐COF‐1 as both the therapeutic boron agent and the nanocarrier co‐delivery of DMXAA and Ce6. This nanoplatform achieved synergistic tumor‐specific boron delivery, real‐time pharmacokinetic monitoring, and immunomodulation.
Yiming Liu, Xuejian Wang, Bangjian Li, Kun Shao, Jianlong Su, Yang Wang, Lin Cheng, Zhihao Wu, JinRong Li, Guanyi Zhang, Xu Wang, Yuxuan Zhang, Yuanhao Liu, Guangzhe Li   +13 more
wiley   +1 more source