Results 201 to 210 of about 1,844,829 (280)

Ion Channels as Therapeutic Targets in Overactive Bladder: A Narrative Review of Mechanisms, Translational Evidence, and Current Gaps. [PDF]

Low Urin Tract Symptoms
Demirçi B, Helvacı G, Barut EN, Engin S.   +3 more
europepmc   +1 more source

Sensing‐Integrated Patient‐Derived Tumorspheres Predict Chemotherapeutic Efficacy via Local Extracellular pH Dynamics

Small, EarlyView.
The study introduces a 3D sensing‐integrated platform enabling real‐time, non‐invasive monitoring of pH dynamics in patient‐derived PDAC tumorspheres. It revealed distinct extracellular acidification patterns under FOLFIRINOX, gemcitabine, and paclitaxel, correlating with therapeutic efficacy.
Stefania Forciniti, Valentina Onesto, Anna Chiara Siciliano, Helena Iuele, Stefano D'Ugo, Norma Depalma, Cinzia Fasano, Alessandro D'Amuri, Giuseppe Gigli, Marcello G. Spampinato, Loretta L. del Mercato   +10 more
wiley   +1 more source

Bioelectrical Regulation of Vascular Endothelial Function in Atherosclerosis. [PDF]

Biomolecules
Custodio JM, Liu JJ, Zhang L, Hong L.
europepmc   +1 more source

Fluorescence Sensing of Anions Like Adenosine 5ʹ‐Triphosphate With pH‐Gated Porous Dye‐Loaded Cerasomes

Small, EarlyView.
The development of gated systems enabling controlled pore opening offers new opportunities for sensing applications. This study explores dye loading in porous and non‐porous cerasomes and pH‐dependent ATP‐triggered gating via polyamine anchors. Porous cerasomes were synthesized using block‐co‐polymers, enabling controlled proton influx and fluorescence‐
Romane Vinot, Estela Climent, Maja Friedrich, Jérémy Bell, Knut Rurack   +4 more
wiley   +1 more source

Bioelectronic Wearable Sensors Produced by Computerized Embroidery Using a Dual Thread Approach

Small, EarlyView.
A dual‐thread embroidered SmartBra integrates silver‐plated and conductive‐polymer (PECOTEX) threads to enable simultaneous cardiac monitoring and open‐circuit potentiometric sensing of potassium and sodium in a breast milk substitute. The wearable platform is fabricated using computerized embroidery, offering a scalable, proof‐of‐concept route toward ...
Taliya Weinstein, Xintong Li, Hasan Kurt, Selin Olenik, Alexander Silva‐Pinto Collins, José Manuel Rodrigueiro Flauzino, Muhammed Adeel, Laura Gonzalez‐Macia, Meral Yüce, Firat Güder   +9 more
wiley   +1 more source

Temperature dependence of HCN channel kinetics: A systematic comparison across mammalian isoforms and species. [PDF]

Exp Physiol
Ranjan R, Logette E, Herzog M, Buchillier V, Scantamburlo E, Markram H.   +5 more
europepmc   +1 more source

ON/OFF Phenomenon in 4‐Aminopyridine Therapy in Spinocerebellar Ataxia 27B: Therapeutic and Diagnostic Insights

Movement Disorders Clinical Practice, EarlyView.
Chiara Caneda, Eleonora Bertoncello, Alessia Peghin, Sara Satolli, Filippo Maria Santorelli, Michele Tinazzi, Ilaria Antonella Di Vico   +6 more
wiley   +1 more source

Smart cellulose‐based room temperature phosphorescent materials: From mechanisms to construction strategies and applications

Smart Molecules, EarlyView.
This review elucidates the photophysical mechanisms of cellulose‐based room temperature phosphorescent materials and systematically outlines their construction strategies, such as cluster emission center engineering. This article demonstrates their applications in fields like information encryption and bioimaging, and looks ahead to the core challenges
Shasha Wu, Yifan Zhou, Wanjin Wu, Yan Tang, Mengfan Jing, Jianyu Zhang, Haoke Zhang, Zheng Zhao, Junwei Wang, Laurent Maron, Lijie Liu   +10 more
wiley   +1 more source

Boron‐embedded multifunctional nanoplatform toward potential combined boron neutron capture therapy and immunomodulation in glioma

Smart Molecules, EarlyView.
A brain‐targeting multifunctional nanoplatform (DM&Ce6@COF‐Ang) was engineered by employing boron‐enriched APTES‐COF‐1 as both the therapeutic boron agent and the nanocarrier co‐delivery of DMXAA and Ce6. This nanoplatform achieved synergistic tumor‐specific boron delivery, real‐time pharmacokinetic monitoring, and immunomodulation.
Yiming Liu, Xuejian Wang, Bangjian Li, Kun Shao, Jianlong Su, Yang Wang, Lin Cheng, Zhihao Wu, JinRong Li, Guanyi Zhang, Xu Wang, Yuxuan Zhang, Yuanhao Liu, Guangzhe Li   +13 more
wiley   +1 more source

One model to rule them all: Unification of voltage-gated potassium channel models via deep non-linear mixed effects modelling. [PDF]

PLoS Comput Biol
Linkevicius D, Chadwick A, Stefan MI, Sterratt DC.   +3 more
europepmc   +1 more source