Results 221 to 230 of about 1,844,829 (280)

Bacterial Communication: The Possible Role of Quorum Sensing, Quantum Mechanics, and Quantum Tunneling. [PDF]

Metabolites
Dicks LMT, Pohl C, Botha A.
europepmc   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

Epilepsy as a Multiscale Network Disorder: Integrating Precision Therapeutics and Emerging Experimental Platforms. [PDF]

Pharmaceutics
Chang W, Kwak AS, Han SH, Song DY, Yoo HI, Lee JH.   +5 more
europepmc   +1 more source

Kcnv2 E151X Mouse Captures Hallmarks of KCNV2‐Associated Retinal Dystrophy

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background KCNV2‐associated retinopathy is a rare inherited retinal dystrophy caused by variants in the KCNV2 gene, leading to disrupted photoreceptor behaviour and progressive deterioration of vision. Patients have characteristic electroretinography abnormalities, including reduced cone response, delayed and reduced rod response to low light ...
Nermina Xhaferri, Sumit Biswas, Benjamin Davies, Moritz Lindner   +3 more
wiley   +1 more source

Immediate Effects of Magnetic Stimulation on Dentate Gyrus Glutamatergic and GABAergic Neuron Excitability. [PDF]

Brain Sci
Ren Z, Lu B, Qiu H, Wang Z, Wang T, Kang J, Zou T, Zhu H, Ding C.   +8 more
europepmc   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

Gating crosstalk in potassium channels. [PDF]

Proc Natl Acad Sci U S A
Hu L, de Groot BL, Gu RX.
europepmc   +1 more source

The Role of the Glutamate-Glutamine Cycle in Synaptic Transmission During Ischemia and Recovery. [PDF]

Eur J Neurosci
van Susteren H, Rose CR, van Putten MJAM, Meijer HGE.   +3 more
europepmc   +1 more source

A computational model of altered neuronal activity in altered gravity. [PDF]

NPJ Microgravity
Gontier C, Drouvé L, Striebel J, Sturm M, Meerholz Z, Schunk S, Lichterfeld Y, Liemersdorf C.   +7 more
europepmc   +1 more source

K_V3.1 channel modulation: a systematic review of pharmacological intervention strategies. [PDF]

Front Pharmacol
Nuñez E, Muguruza-Montero A, Arrizabalaga-Iriondo A, Zayas-Arrabal J, M-Alicante S, Urrutia J, Revuelta M.   +6 more
europepmc   +1 more source