Results 231 to 240 of about 1,844,829 (280)

Nausea, Fatigue, and T-Wave Inversion: An Electrocardiographic Challenge. [PDF]

JACC Case Rep
Kurop M, Khoukaz HB, Fay WP.
europepmc   +1 more source

The electrical tumor microenvironment: abnormalities and opportunities. [PDF]

Front Oncol
Burchett Darantiere A, Lay F, Datta M.
europepmc   +1 more source

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Voltage-gated Potassium Channel Inhibitors

Current Pharmaceutical Design, 1996
Forty years have transpired since tetraethylammonium was first used to selectively inhibit the potassiuin conductance in squid axons. Since then, a large body of work has emerged describing inhibitors of voltage-gated potassium currents in a variety of cells.
W. F. Hopkins, J. L. Miller, G. P. Miljanich   +2 more
exaly   +2 more sources

The structure of a voltage gated potassium channel [PDF]

, 2010
Voltage gated potassium channels (Kv channels) are tetrameric ion channels, responsible for regulating the potassium component of the membrane potential in a large range of cell types ranging from mammalian excitable cells to bacteria. Attempts have been made to elucidate the structure of voltage gated potassium channels using X-ray crystallography ...
Rogers, Nik
core   +2 more sources

Mechanism of Voltage Gating in Potassium Channels

Science, 2012
Open and Shut Case Voltage-sensing domains (VSDs) control the activity of voltage-gated ion channels to regulate the ion flow that underlies nerve conduction. Structural and biophysical studies have provided insight into voltage gating; however, understanding has been hindered by the lack of a crystal structure of a fully closed ...
Morten Ø, Jensen, Vishwanath, Jogini, David W, Borhani, Abba E, Leffler, Ron O, Dror, David E, Shaw   +5 more
openaire   +2 more sources

Thermodynamics of a voltage-gated potassium channel

Physical Review E
In order to know how a single potassium channel works in its microscopic niche, a hybrid process about the observables of channel state and voltage is constructed, which comprises the interweaving kinetics of channel gating, voltage decay, and thermal noise. The formula of entropy production rates (i.e., power dissipation) is derived and the stationary
Jia-Zeng Wang, PengKun Hu, YueYing Zheng, YuMei Li   +3 more
openaire   +3 more sources

The voltage-gated potassium channels and their relatives

Nature, 2002
The voltage-gated potassium channels are the prototypical members of a family of membrane signalling proteins. These protein-based machines have pores that pass millions of ions per second across the membrane with astonishing selectivity, and their gates snap open and shut in milliseconds as they sense changes in voltage or ligand concentration.
openaire   +2 more sources

Voltage-Gated Potassium Channels in Cell Proliferation

Physiology, 2004
It is commonly accepted that cells require K+channels to proliferate. The role(s) of K+channels in the process is, however, poorly understood. Cloning of K+channel genes opened the possibility to approach this problem in a way more independent from pharmacological tools.
openaire   +3 more sources