Results 21 to 30 of about 66,281 (214)

Gene Silencing of Toll-like Receptor 2 Gene Expression as a Tactic to Control Mycobacterium Tuberculosis and Granuloma Formation [PDF]

Archives of Razi Institute, 2022
Mycobacterium tuberculosis (MT) is the causative agent of tuberculosis (TB) in humans. Tuberculosis is one of the top 10 causes of mortality worldwide, resulting in 1.8 million deaths and 10.4 million new cases in 2016.
M. A Nama
doaj   +1 more source

PPARβ/δ and PPARγ maintain undifferentiated phenotypes of mouse adult neural precursor cells from the subventricular zone [PDF]

Frontiers in Cellular Neuroscience, 2015
The subventricular zone (SVZ) is one of the main niches of neural stem cells in the adult mammalian brain. Stem and precursor cells in this region are the source for neurogenesis and oligodendrogesis, mainly in the olfactory bulb and corpus callosum, respectively.
Carolina eBernal, Carolina eBernal, Claudia eAraya, Veronica ePalma, Miguel eBronfman   +4 more
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PPARγ signaling is required for mediating EETs protective effects in neonatal cardiomyocytes exposed to LPS [PDF]

Frontiers in Pharmacology, 2014
Lipopolysaccharide (LPS) is a bacterial wall endotoxin producing many pathophysiological conditions including myocardial inflammation leading to cardiotoxicity. Epoxyeicosatrienoic acids (EETs) are biologically active metabolites of arachidonic acids capable of activating protective cellular pathways in response to stress stimuli. EETs evoke a plethora
Victor eSamokhvalov, Jelle eVriend, Jelle eVriend, Kristi L Jamieson, Maria eAkhnokh, Rajkumar eManne, John R Falck, John M. Seubert, John M. Seubert   +8 more
openaire   +3 more sources

Exercise retards ongoing adipose tissue fibrosis in diet-induced obese mice

Endocrine Connections, 2021
Exercise has been recommended as an important strategy to impro ve glucose metabolism in obesity. Adipose tissue fibrosis is associated with inflammati on and is implicated in glucose metabolism disturbance and insulin resistance in obesit y.
Liangming Li, Yuan Wei, Chunlu Fang, Shujing Liu, Fu Zhou, Ge Zhao, Yaping Li, Yuan Luo, Ziyi Guo, Weiqun Lin, Wenqi Yang   +10 more
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The use of telmisartan in patients with refractory arterial hypertension and obesity

Кардиоваскулярная терапия и профилактика, 2019
Aim. To evaluate the effectiveness of telmisartan as a component of triple antihypertensive therapy in patients with obesity and refractory arterial hypertension.Material and methods.
I. Е. Deneka, A. V. Rodionov, V. V. Fomin   +2 more
doaj   +1 more source

Rice consumption and predisposition to metabolic diseases: The role of PPARγ and GLUT4 dysregulation

Journal of Nutrition & Intermediary Metabolism, 2017
Metabolic diseases of significant dietary cause have been multiplying since the climax of the Industrial Revolution and are approaching pandemic proportions. Diet has been promulgated as a cornerstone in tackling these diseases. Understanding the long-term molecular modulatory functions of a diet on key metabolic pathways associated with the ...
Bilyaminu Abubakar, Norsharina Ismail, Abdul Rahman Omar, Md Zuki Abu bakar, Maznah Ismail   +4 more
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Localization of peroxisome proliferator-activated receptor alpha (PPARα) and N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) in cells expressing the Ca2+-binding proteins calbindin, calretinin, and parvalbumin in the adult rat hippocampus [PDF]

Frontiers in Neuroanatomy, 2014
The N-acylethanolamines (NAEs), oleoylethanolamide (OEA) and palmithylethanolamide (PEA) are known to be endogenous ligands of PPARα receptors, and their presence requires the activation of a specific phospholipase D (NAPE-PLD) associated with intracellular Ca(2+) fluxes.
Rivera, Patricia, Arrabal, Sergio, Vargas, Antonio, Blanco Calvo, Eduardo, Serrano, Antonia, Pavón, Francisco Javier, Rodríguez de Fonseca, Fernando, Suárez, Juan   +7 more
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PPAR γ/TLR4/TGF-β1 axis mediates the protection effect of erythropoietin on cyclosporin A-induced chronic nephropathy in rat

Renal Failure, 2020
Objective Nephrotoxicity is the main side effect of cyclosporine A and finding an effective combating method is urgent. The present study investigates the improving effect of erythropoietin (EPO) on cyclosporine A induce renal injury in rats and further ...
Bin Liu, Ping Tan
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WITHDRAWN: Mouse Trefoil Factor 3 (Tff3) Ameliorates Fatty Liver Phenotype via Increasing Peroxisome Proliferator-activated Receptor-α (PPARα) Expression

Oncotarget, 2017
// Xiaojie Wu 1, * , Haiyong Jin 2, * , Yueling Zhang 3 , Mingyuan Dong 3 , Xiaoting Wu 3 , Jiadi Zhou 1 , Weishan Zhuge 4 , Jianjing Yang 5 , Qichuan Zhuge 5 , Xiying Luan 1 , Dexiang Ban 6 , Wenjie Zhu 3 , Yongjun Jin 7 and Jiangnan Xue 1 1 Department of Immunology, Binzhou Medical University, Yantai, China 2 Department of ...
Xiaojie Wu, Xiaojie Wu, Haiyong Jin, Haiyong Jin, Yueling Zhang, Yueling Zhang, Mingyuan Dong, Mingyuan Dong, Xiaoting Wu, Xiaoting Wu, Jiadi Zhou, Jiadi Zhou, Weishan Zhuge, Weishan Zhuge, Jianjing Yang, Jianjing Yang, Qichuan Zhuge, Qichuan Zhuge, Xiying Luan, Xiying Luan, Dexiang Ban, Dexiang Ban, Wenjie Zhu, Wenjie Zhu, Yongjun Jin, Yongjun Jin, Jiangnan Xue, Jiangnan Xue   +27 more
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Anti‐diabetic effect of andrographolide from Sambiloto herbs (Andrographis paniculata (Burm.f.) Nees) through the expression of PPARγ and GLUT‐4 in adipocytes

Indonesian Journal of Biotechnology, 2022
Andrographolide has been shown to have a pharmacological effect as an antidiabetic. Nevertheless, the comprehensive mechanism of action has yet to be determined.
Novia Tri Astuti, Putri Rachma Novitasari, Raymond Tjandrawinata, Agung Endro Nugroho, Suwijiyo Pramono   +4 more
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