Results 31 to 40 of about 121,549 (307)

WITHDRAWN: Mouse Trefoil Factor 3 (Tff3) Ameliorates Fatty Liver Phenotype via Increasing Peroxisome Proliferator-activated Receptor-α (PPARα) Expression

Oncotarget, 2017
// Xiaojie Wu 1, * , Haiyong Jin 2, * , Yueling Zhang 3 , Mingyuan Dong 3 , Xiaoting Wu 3 , Jiadi Zhou 1 , Weishan Zhuge 4 , Jianjing Yang 5 , Qichuan Zhuge 5 , Xiying Luan 1 , Dexiang Ban 6 , Wenjie Zhu 3 , Yongjun Jin 7 and Jiangnan Xue 1 1 Department of Immunology, Binzhou Medical University, Yantai, China 2 Department of ...
Xiaojie Wu, Xiaojie Wu, Haiyong Jin, Haiyong Jin, Yueling Zhang, Yueling Zhang, Mingyuan Dong, Mingyuan Dong, Xiaoting Wu, Xiaoting Wu, Jiadi Zhou, Jiadi Zhou, Weishan Zhuge, Weishan Zhuge, Jianjing Yang, Jianjing Yang, Qichuan Zhuge, Qichuan Zhuge, Xiying Luan, Xiying Luan, Dexiang Ban, Dexiang Ban, Wenjie Zhu, Wenjie Zhu, Yongjun Jin, Yongjun Jin, Jiangnan Xue, Jiangnan Xue   +27 more
openaire   +1 more source

Anti‐diabetic effect of andrographolide from Sambiloto herbs (Andrographis paniculata (Burm.f.) Nees) through the expression of PPARγ and GLUT‐4 in adipocytes

Indonesian Journal of Biotechnology, 2022
Andrographolide has been shown to have a pharmacological effect as an antidiabetic. Nevertheless, the comprehensive mechanism of action has yet to be determined.
Novia Tri Astuti, Putri Rachma Novitasari, Raymond Tjandrawinata, Agung Endro Nugroho, Suwijiyo Pramono   +4 more
doaj   +1 more source

PPAR gamma/mTOR signalling: striking the right balance in cartilage homeostasis [PDF]

, 2015
This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work ...
Afif, Betz, Boileau, Caramés, Chen, Damyanovich, Francesco Dell'Accio, Glasson, Jacinto, Joanna Sherwood, Johnson, Kim, Laplante, Miller, Reginster, Saito, Sampson, Sarbassov, Sherwood, Vasheghani, Vasheghani, Yang, Yin, Zhang   +23 more
core   +2 more sources

Obesity-linked PPARγ S273 phosphorylation promotes insulin resistance through Growth Differentiation Factor 3

bioRxiv, 2020
Overnutrition and obesity promote adipose tissue dysfunction, often leading to systemic insulin resistance. The thiazolidinediones (TZDs) are a potent class of insulin-sensitizing drugs and ligands of PPARγ that improve insulin sensitivity, but their use
J. Hall, Deepti Ramachandran, H. Roh, J. DiSpirito, Thiago Belchior, Peter-James H. Zushin, Colin J. Palmer, Shangyu Hong, Amir I. Mina, Bingyang Liu, Zhaoming Deng, Pratik Aryal, Christopher Jacobs, Danielle E. Tenen, Chester W. Brown, J. Charles, G. Shulman, B. Kahn, Linus T. Tsai, E. Rosen, B. Spiegelman, Alexander S. Banks   +21 more
semanticscholar   +1 more source

Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): Astragaloside IV (AS-IV) is a bioactive saponin with a wide range of pharmacological effects. This study was aimed at investigating its potential effect on polycystic ovary syndrome (PCOS).
Mingxiao Wen, Wenjun Chen, Qun Zhou, Xiaoqing Dou   +3 more
doaj   +1 more source

Rice consumption and predisposition to metabolic diseases: The role of PPARγ and GLUT4 dysregulation

Journal of Nutrition & Intermediary Metabolism, 2017
Metabolic diseases of significant dietary cause have been multiplying since the climax of the Industrial Revolution and are approaching pandemic proportions. Diet has been promulgated as a cornerstone in tackling these diseases. Understanding the long-term molecular modulatory functions of a diet on key metabolic pathways associated with the ...
Bilyaminu Abubakar, Norsharina Ismail, Abdul Rahman Omar, Md Zuki Abu bakar, Maznah Ismail   +4 more
openaire   +2 more sources

PENGARUH PEMBERIAN OX-LDL TERHADAP AKTIVASI NF-кB DAN PPARγ γγ γSERTA APOPTOSIS PADA KULTUR HUVEC’s

Jurnal Kedokteran Brawijaya, 2013
Oxidized LDL (ox-LDL) causes activation and dysfunction of endothelial cells through NFκB activation after binding process of ox-LDL to LOX-1. One of ox-LDL components had been known as the activator of PPARγ. This study was done to see the effect of ox-LDL on NFκB and PPARγactivation and apoptosis of HUVEC’s culture.
Wibi Riawan, Samodijanti Wibowati
openaire   +2 more sources

Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cells and obese rodent model [PDF]

Royal Society Open Science, 2021
Accumulating evidence suggests that mitochondrial dysfunction and adipocyte differentiation promote lipid accumulation in the development of obesity and diabetes.
Dandan Zhao, Yanyun Pan, Na Yu, Ying Bai, Rufeng Ma, Fangfang Mo, Jiacheng Zuo, Beibei Chen, Qiangqiang Jia, Dongwei Zhang, Jiaxian Liu, Guanjian Jiang, Sihua Gao   +12 more
doaj   +1 more source

Thiazolidinediones/PPARγ agonists and fatty acid synthase inhibitors as an experimental combination therapy for prostate cancer

International Journal of Oncology, 2011
The prostate cancer (PCa) cell lines LNCaP, PC-3, and DU-145 express peroxisome proliferator-activated receptor γ (PPARγ) but its role in PCa is unclear. Thiazolidinediones (TZDs), a family of PPARγ activators and type 2 anti-diabetic drugs, exhibit anti-tumor apoptotic effects in human PCa cell lines. Likewise, pharmacological inhibitors of fatty acid
Mahmoud, Mansour, Dean, Schwartz, Robert, Judd, Benson, Akingbemi, Tim, Braden, Edward, Morrison, John, Dennis, Frank, Bartol, Amanda, Hazi, India, Napier, Asim B, Abdel-Mageed   +10 more
openaire   +3 more sources

STK38 is a PPARγ-interacting protein promoting adipogenesis

Adipocyte, 2021
Peroxisome proliferator-activated receptor-γ (PPARγ) is the master regulator of adipogenesis, but knowledge about how PPARγ is regulated at the protein level is very limited.
Kun Qian, Daozhan Yu, Weiming Wang, Mengqi Jiang, Rongze Yang, Robert Brown, Da-Wei Gong   +6 more
doaj   +1 more source