Results 21 to 30 of about 1,781,780 (142)

Integrated signaling pathway and gene expression regulatory model to dissect dynamics of Escherichia coli challenged mammary epithelial cells [PDF]

open access: yes, 2014
Cells transform external stimuli, through the activation of signaling pathways, which in turn activate gene regulatory networks, in gene expression. As more omics data are generated from experiments, eliciting the integrated relationship between the ...
den Breems, NY   +4 more
core   +1 more source

Cordycepin can improve Pulmonary Arterial Hypertension in Rats via cGMP/PKG/PPAR-γ Signaling Pathway

open access: yes, 2022
 In conclusion, Cordycepin may improve rat PAH and other specific mechanisms by enhancing the cGMP/PKG/PPAR-γ signaling pathway. 
Department of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou, China.   +1 more
core   +1 more source

Expanding the Hippo pathway : hMOB3 modulates apoptotic MST1 signaling and supports tumor growth in glioblastoma [PDF]

open access: yes, 2014
Protein kinases are critical players of signal transduction pathways involved in development, physiological and pathological processes. Deregulation of protein kinase signaling is found to be causal or related to varieties of human diseases, such as ...
Tang, Fengyuan
core   +1 more source

Enrichment of the PPAR signaling pathway in muscle from Iberian fetuses.

open access: yes, 2020
Enrichment of the PPAR signaling pathway in muscle from Iberian fetuses.
Adrián López-García (8367708)   +12 more
core   +1 more source

Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]

open access: yes, 2002
Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G.   +5 more
core   +1 more source

Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis [PDF]

open access: yes, 2010
The transcription factor peroxisome proliferator-activated receptor alpha (PPARalpha) is an important regulator of hepatic lipid metabolism. While PPARalpha is known to activate transcription of numerous genes, no comprehensive picture of PPARalpha ...
Degenhardt, Tatjana   +35 more
core   +1 more source

Pharmacological studies of a novel inhibitor of the mammalian target of rapamycin (mTOR) signaling pathway [PDF]

open access: yes, 2010
The apoptotic mode of cell death (programmed cell death) is an active and defined process that plays an important role in the development of multicellular organisms and in the regulation and maintenance of cell populations in tissues under physiologic ...
Morad, Samy
core   +1 more source

Pathway of PPAR signaling pathway.

open access: yes, 2015
Pathway of PPAR signaling pathway.
Liqiao Chen (322720)   +6 more
core   +1 more source

Loss of FTO Antagonises Wnt Signaling and Leads to Developmental Defects Associated with Ciliopathies [PDF]

open access: yes, 2014
Common intronic variants in the Human fat mass and obesity-associated gene (FTO) are found to be associated with an increased risk of obesity. Overexpression of FTO correlates with increased food intake and obesity, whilst loss-of-function results in ...
Rosa Maria Roccasecca (519728)   +40 more
core   +1 more source

"Drosophila" genetics as a tool in the search for novel components of the S6 kinase signaling pathway [PDF]

open access: yes, 2009
Signaling events that converge on the activation of the TOR/S6K pathway have been shown to be critically related to growth. Recent investigations on the molecular network controlling growth have revealed that Drosophila melanogaster constitutes an ...
Bennion, Janis Michelle
core   +1 more source

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