Results 101 to 110 of about 27,504 (316)
Mimicking the surface and prebiotic chemistry of early Earth using flow chemistry
Nature Communications, 2018 There is still much debate on early Earth geochemical conditions affecting the chemistry of simple synthons that originated life. Here, the authors report an uninterrupted multistep synthetic route to 2-aminooxazole by means of flow chemistry equipment ...
Dougal J. Ritson +3 more
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Chemistry of Homocysteine Thiolactone in A Prebiotic Perspective
Life, 2019 Homocysteine is a non-proteinogenic sulfur-containing amino acid. Like cysteine, it can form disulfide bridges and complex metallic cations. It is also closely related to methionine, the first amino acid in the synthesis of all contemporary proteins ...
Ibrahim Shalayel, Yannick Vallée
doaj +1 more source
Multiple prebiotic metals mediate translation. [PDF]
, 2018 Today, Mg2+ is an essential cofactor with diverse structural and functional roles in life's oldest macromolecular machine, the translation system. We tested whether ancient Earth conditions (low O2, high Fe2+, and high Mn2+) can revert the ribosome to a ...
Bowman, Jessica C +8 more
core +1 more source
Perinatal Gut Dysbiosis Reduces Milk Oligosaccharides via LPS‐Mediated Gut–Mammary Signaling in Mice
Food Frontiers, EarlyView.Maternal gut dysbiosis elevates Gram‐negative bacterial lipopolysaccharide (LPS), which enters circulation and accumulates in mammary tissue. This compromises the blood–milk barrier and suppresses key enzymatic genes, ultimately reducing milk oligosaccharide synthesis and potentially affecting neonatal gut microbiota through breastfeeding.
Man‐Lin Zhou +9 more
wiley +1 more source
Harnessing prebiotic formamide chemistry: a novel platform for antiviral exploration
Scientific ReportsViruses and host cells are intricately connected through a shared “chemical language” that may trace back to the prebiotic chemistry of early Earth. In this study, we present an innovative platform for antiviral exploration inspired by this primordial ...
Maria Grazia Martina +10 more
doaj +1 more source
CONNECTING PREBIOTIC CHEMISTRY IN THE LABORATORY TO PROTOSTELLAR OBSERVATIONS [PDF]
, 2023 Will Thompson, Susanna L. Widicus Weaver
openalex +1 more source
Prebiotic chemistry: A fuzzy field
Comptes Rendus. Chimie, 2010 If prebiotic chemistry is defined as the study of the chemical steps, which lead to the first organisms, a clear-cut definition of “living organism” is needed. Unfortunately, no unambiguous and universally accepted definition exists for the concept “living”.
Bruylants, Gilles +2 more
openaire +1 more source
Food Frontiers, EarlyView.‐Pi infusion significantly improved locomotor activity and exploratory behavior in aging mice; its bioactive compounds may have direct effects on behavior, which may be accompanied by a putative indirect effect involving the gut microbiota. ‐Pi infusion consumption restored commensal Bacilli levels and caused a significant decrease in Clostridia levels
Yulia Kroupitski +7 more
wiley +1 more source
Adenine and Thymine Effect on Quartz Dissolution at Different Artificial Seawaters
Orbital: The Electronic Journal of Chemistry, 2018 According to Bernal (1951) minerals may have played important roles in the origin of life such as: protect biomolecules against degradation by UV radiation or hydrolysis, pre-concentrate biomolecules from prebiotic seas and formation of polymers.
Dimas Augusto Morozin Zaia +2 more
doaj +3 more sources
Food Frontiers, EarlyView.This review highlights recent biotechnological innovations in the valorization of food waste through enzyme‐assisted processing and microbial fermentation to enhance nutritional, techno‐functional, and shelf‐stable properties for developing sustainable, plant‐based functional foods and nutraceuticals.
Md. Sakhawot Hossain +6 more
wiley +1 more source