Results 71 to 80 of about 31,847 (287)

Generic Strategies for Chemical Space Exploration [PDF]

, 2014
Computational approaches to exploring "chemical universes", i.e., very large sets, potentially infinite sets of compounds that can be constructed by a prescribed collection of reaction mechanisms, in practice suffer from a combinatorial explosion.
Andersen, Jakob L., Flamm, Christoph, Merkle, Daniel, Stadler, Peter F.   +3 more
core   +1 more source

Frontiers in Prebiotic Chemistry and Early Earth Environments

Origins of Life and Evolution of Biospheres, 2022
The Prebiotic Chemistry and Early Earth Environments (PCE3) Consortium is a community of researchers seeking to understand the origins of life on Earth and in the universe. PCE3 is one of five Research Coordination Networks (RCNs) within NASA's Astrobiology Program.
Müller, U.F., Elsila, J., Trail, D., DasGupta, S., Giese, C.C., Walton, C.R., Cohen, Z.R., Stolar, T., Krishnamurthy, R., Lyons, T.W., Rogers, K.L., Williams, L.D.   +11 more
openaire   +5 more sources

Supramolecular Gels as Active Tools for Reaction Engineering

Angewandte Chemie, EarlyView.
The unique combination of environments within gels, self‐assembled from low‐molecular‐weight gelators, offers the ability to control reactivity in new ways, achieving unique reaction outcomes, leading to the emerging concept of supramolecular gels as nanoreactors. Smart chemical engineering methods enable the use of such gels to fabricate materials and
David K. Smith
wiley   +2 more sources

Chemical Diversity of Metal Sulfide Minerals and Its Implications for the Origin of Life

Life, 2018
Prebiotic organic synthesis catalyzed by Earth-abundant metal sulfides is a key process for understanding the evolution of biochemistry from inorganic molecules, yet the catalytic functions of sulfides have remained poorly explored in the context of the ...
Yamei Li, Norio Kitadai, Ryuhei Nakamura
doaj   +1 more source

The Influence of Galactic Cosmic Rays on Ion-Neutral Hydrocarbon Chemistry in the Upper Atmospheres of Free-Floating Exoplanets [PDF]

, 1989
Cosmic rays may be linked to the formation of volatiles necessary for prebiotic chemistry. We explore the effect of cosmic rays in a hydrogen-dominated atmosphere, as a proof-of-concept that ion-neutral chemistry may be important for modelling hydrogen ...
C. Bilger, Ch. Helling, Miller, P. B. Rimmer, Rimmer, Skilling   +5 more
core   +3 more sources

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

Advanced Therapeutics, EarlyView.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap, Pankaj R. Khuspe, Sagar R. Pardeshi, Md Jasim Uddin, Ushasi Das, Navnath T. Hatvate, Satish Rojekar, Prabhanjan Giram, Mohammad Khalid, Yahya E. Choonara, Md. Faiyazuddin   +10 more
wiley   +1 more source

Environmental History is Transferred via Minerals Altering Formose Reaction Pathways

Angewandte Chemie, EarlyView.
We study the influence of minerals on the formose reaction. We found that different minerals have distinct impact on the network outcome effects, that change over sequential batch reactions, demonstrating a history effect. Finally, we show that when minerals are first incubated with the aqueous catalysts, they subsequently allow for formation of ...
Thijs J. de Jong, Astra D. Demertzi, William E. Robinson, Wilhelm T. S. Huck   +3 more
wiley   +2 more sources

The Prevailing Catalytic Role of Meteorites in Formamide Prebiotic Processes

Life, 2018
Meteorites are consensually considered to be involved in the origin of life on this Planet for several functions and at different levels: (i) as providers of impact energy during their passage through the atmosphere; (ii) as agents of geodynamics ...
Raffaele Saladino, Lorenzo Botta, Ernesto Di Mauro   +2 more
doaj   +1 more source

Toward homochiral protocells in noncatalytic peptide systems

, 2009
The activation-polymerization-epimerization-depolymerization (APED) model of Plasson et al. has recently been proposed as a mechanism for the evolution of homochirality on prebiotic Earth.
A Brack, A Brandenburg, A Brandenburg, A Commeyras, A Lazcano, B-M Rode, C Shen, C Viedma, CJ Welch, D Castelvecchi, D Deamer, D Deamer, D Deamer, D Segrè, D-G Blackmond, D-K Kondepudi, F-C Frank, G Wächtershäuser, G-F Joyce, G-F Joyce, H-J Morowitz, J-A Wattis, J-D Gunton, J-S Langer, J-W Szostak, JD Dunitz, K Soai, L Leman, M Fishkis, M Gleiser, M Gleiser, M Gleiser, M Huber, M Huber, M Reches, M Reches, M-P Robertson, Marcelo Gleiser, N Berclaz, N Berclaz, P-A Monnard, P-G-H Sandars, R Cotterill, R Lathe, R Lathe, R Plasson, R-M Smith, R-P Bywater, S Fox, S Fox, S Fox, S Lonchin, S Rasmussen, S Santoso, S Vauthey, S-L Miller, Sara Imari Walker, UJ Meierhenrich, V-A Avetisov, W-A Bonner, Y Saito, Y Saito   +61 more
core   +1 more source

Prebiotic chemistry: A fuzzy field

Comptes Rendus. Chimie, 2010
If prebiotic chemistry is defined as the study of the chemical steps, which lead to the first organisms, a clear-cut definition of “living organism” is needed. Unfortunately, no unambiguous and universally accepted definition exists for the concept “living”.
Bruylants, Gilles, Bartik, Kristin, Reisse, Jacques   +2 more
openaire   +2 more sources