Results 111 to 120 of about 25,523 (241)

Mutant Presenilin 1 Increases the Expression and Activity of BACE1 [PDF]

, 2009
Luca Giliberto, Roberta Borghi, Alessandra Piccini, Rosa Mangerini, Sandro Sorbi, Gabriella Cirmena, Anna Garuti, Bernardino Ghetti, Fabrizio Tagliavini, Mohamed R. Mughal, Mark P. Mattson, Xiongwei Zhu, Xinglong Wang, Michela Guglielmotto, Elena Tamagno, Massimo Tabaton   +15 more
openalex   +1 more source

Changes in γ-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1 [PDF]

, 2008
Donald B. Carter, Edwige Dunn, Adele M. Pauley, Denise D. McKinley, Timothy J. Fleck, Brenda R Ellerbrook, Nancy C. Stratman, Xiangdong Zhou, Carol S. Himes, Jeffrey S. Nye, Alfredo G. Tomasselli, Riqiang Yan   +11 more
openalex   +1 more source

Author response: Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans

, 2018
Shaarika Sarasija, Jocelyn T. Laboy, Zahra Ashkavand, Jennifer Bonner, Yi Tang, Kenneth R. Norman   +5 more
openalex   +1 more source

Presenilin-dependent Intramembrane Proteolysis of CD44 Leads to the Liberation of Its Intracellular Domain and the Secretion of an Aβ-like Peptide [PDF]

, 2002
Sven Lammich, Masayasu Okochi, Masatoshi Takeda, Christoph Kaether, Anja Capell, Ann-Katrin Zimmer, Dieter Edbauer, Jochen Walter, Harald Steiner, Christian Haass   +9 more
openalex   +1 more source

The Effects of Treadmill Exercise on Cognitive Performance, Brain Mitochondrial Aβ-42, Cytochrome c, SOD-1, 2 and Sirt-3 Protein Expression in Mutant (N141I) Presenilin-2 Transgenic Mice of Alzheimer's Disease

, 2010
Jung‐Hoon Koo, Hyun-Sub Eum, Eun‐Bum Kang, Insu Kwon, Dong-Cheol Yeom, Gil-Young An, Yoo-Sung Oh, Young-Soo Baik, In-Ho Cho, Joon‐Yong Cho   +9 more
openalex   +2 more sources

Molecular Dissection of Domains in Mutant Presenilin 2 That Mediate Overproduction of Amyloidogenic Forms of Amyloid β Peptides [PDF]

, 1998
Taisuke Tomita, Shinya Tokuhiro, Tadafumi Hashimoto, Keiko Aiba, Takaomi C. Saido, Kei Maruyama, Takeshi Iwatsubo   +6 more
openalex   +1 more source

P3–399: The interleukin–1 type–1 receptor is a substrate for presenilin–dependent gamma–secretase cleavage [PDF]

, 2006
Baukje M. Elzinga, Justin V. McCarthy
openalex   +1 more source

Inverse and distinct modulation of tau‐dependent neurodegeneration by presenilin 1 and amyloid‐β in cultured cortical neurons: evidence that tau phosphorylation is the limiting factor in amyloid‐β‐induced cell death [PDF]

, 2007
Julia Leschik, Alfred T. Welzel, Carina Weissmann, Anne Eckert, Roland Brandt   +4 more
openalex   +1 more source

Structure and dynamics of γ-secretase with presenilin 2 compared to presenilin 1

, 2019
Budheswar Dehury, Ning Tang, Tom L. Blundell, Kasper P. Kepp   +3 more
openalex   +2 more sources

Presenilin-1 [PDF]

, 2020
openaire   +1 more source