Phospho-dependent Accumulation of GABABRs at Presynaptic Terminals after NMDAR Activation [PDF]
Cell Reports, 2016 Here, we uncover a mechanism for regulating the number of active presynaptic GABAB receptors (GABABRs) at nerve terminals, an important determinant of neurotransmitter release.
Saad Hannan +3 more
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Altered exocytosis of inhibitory synaptic vesicles at single presynaptic terminals of cultured striatal neurons in a knock-in mouse model of Huntington’s disease [PDF]
Frontiers in Molecular Neuroscience, 2023 Huntington’s disease (HD) is a progressive dominantly inherited neurodegenerative disease caused by the expansion of a cytosine-adenine-guanine (CAG) trinucleotide repeat in the huntingtin gene, which encodes the mutant huntingtin protein containing an ...
Chen Xu +10 more
doaj +2 more sources
Facilitation of neocortical presynaptic terminal development by NMDA receptor activation [PDF]
Neural Development, 2012 Background Neocortical circuits are established through the formation of synapses between cortical neurons, but the molecular mechanisms of synapse formation are only beginning to be understood.
Sceniak Michael P +2 more
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Altered Synaptic Vesicle Release and Ca2+ Influx at Single Presynaptic Terminals of Cortical Neurons in a Knock-in Mouse Model of Huntington’s Disease [PDF]
Frontiers in Molecular Neuroscience, 2018 Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by the abnormal expansion of CAG repeats in the huntingtin (HTT) gene, which leads to progressive loss of neurons starting in the striatum and cortex.
Sidong Chen +8 more
doaj +2 more sources
Nanoscale organization of CaV2.1 splice isoforms at presynaptic terminals: implications for synaptic vesicle release and synaptic facilitation. [PDF]
Biol Chem, 2023 Cingolani LA +4 more
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Intra-axonal Synthesis of SNAP25 Is Required for the Formation of Presynaptic Terminals [PDF]
Cell Reports, 2017 Localized protein synthesis is a mechanism for developing axons to react acutely and in a spatially restricted manner to extracellular signals. As such, it is important for many aspects of axonal development, but its role in the formation of presynapses ...
Andreia F.R. Batista +2 more
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Key differences in regulation of opioid receptors localized to presynaptic terminals compared to somas: Relevance for novel therapeutics. [PDF]
Neuropharmacology, 2023 Coutens B, Ingram SL.
europepmc +2 more sources
Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies. [PDF]
J Biol Chem, 2021 Weston LJ +9 more
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Distinct functional developments of surviving and eliminated presynaptic terminals. [PDF]
Proc Natl Acad Sci U S A, 2021 Midorikawa M, Miyata M.
europepmc +3 more sources
Opposing functions for retromer and Rab11 in extracellular vesicle traffic at presynaptic terminals. [PDF]
J Cell Biol, 2021 Walsh RB +13 more
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