Results 21 to 30 of about 87,423 (320)
Synaptic actions of amyotrophic-lateral-sclerosis-associated G85R-SOD1 in the squid giant synapse [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Song, Y.
Song, Yuyu
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Specific disruption of hippocampal mossy fiber synapses in a mouse model of familial Alzheimer's disease. [PDF]
, 2014 The earliest stages of Alzheimer's disease (AD) are characterized by deficits in memory and cognition indicating hippocampal pathology. While it is now recognized that synapse dysfunction precedes the hallmark pathological findings of AD, it is unclear ...
Antonios, Joseph K +6 more
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Similarity and Diversity of Presynaptic Molecules at Neuromuscular Junctions and Central Synapses
Biomolecules, 2022 Synaptic transmission is essential for controlling motor functions and maintaining brain functions such as walking, breathing, cognition, learning, and memory.
Kenji Takikawa, Hiroshi Nishimune
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Editorial: Molecular Nanomachines of the Presynaptic Terminal [PDF]
Frontiers in Synaptic Neuroscience, 2016 Cell biology and neurobiology have started many decades ago as attempts to unravel the complexity of cellular processes, by studying different elements, from membranes and organelles to molecules in isolation. Through ever increasing technological improvements, a huge amount of information has accumulated on the molecular organization of the cell, and ...
Rizzoli, Silvio O., Tabares, Lucía
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Frontiers in Neural Circuits, 2022 Modulation of the release of glutamate by activation of presynaptic nicotinic acetylcholine receptors (nAChRs) is one of the most prevalent mechanism of nicotinic facilitation of glutamatergic transmission in cortico-limbic circuits.
Chongbo Zhong +3 more
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Nanoscale-targeted patch-clamp recordings of functional presynaptic ion channels [PDF]
, 2013 Important modulatory roles have been attributed to presynaptic NMDA receptors (NMDARs) located on cerebellar interneuron terminals. Evidence supporting a presynaptic location includes an increase in the frequency of mini events following the application ...
Benton, DCH +4 more
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eLife, 2016 Communication between pre- and postsynaptic cells promotes the initial organization of synaptic specializations, but subsequent synaptic stabilization requires transcriptional regulation.
Akiko Terauchi +4 more
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PSD-95 Is Associated with the Postsynaptic Density and Not with the Presynaptic Membrane at Forebrain Synapses [PDF]
, 1996 PSD-95, a prominent protein component of the postsynaptic density (PSD) fraction from rat forebrain, has been localized by light microscopy to dendrites of hippocampal neurons (Cho et al., 1992) and to the presynaptic plexus of cerebellar basket cells ...
Hunt, Carol A. +2 more
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Invaginating Structures in Mammalian Synapses
Frontiers in Synaptic Neuroscience, 2018 Invaginating structures at chemical synapses in the mammalian nervous system exist in presynaptic axon terminals, postsynaptic spines or dendrites, and glial processes. These invaginating structures can be divided into three categories.
Ronald S. Petralia +3 more
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Presynaptic inhibition of dopamine neurons controls optimistic bias
eLife, 2021 Regulation of reward signaling in the brain is critical for appropriate judgement of the environment and self. In Drosophila, the protocerebral anterior medial (PAM) cluster dopamine neurons mediate reward signals. Here, we show that localized inhibitory
Nobuhiro Yamagata +4 more
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