Prion-like protein propagation in neurodegenerative diseases
Hasegawa, Masato +8 more
openaire +3 more sources
Proteína prion celular (PrPc) altera a suscetibilidade ao etanol através da modulação do sistema dopaminérgico [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em FarmacologiaO consumo de drogas com potencial aditivo, como o etanol, induz alterações sinápticas profundas na via mesocorticolímbica ...
Rial, Daniel
core
Prion Protein Scrapie and the Normal Cellular Prion Protein
Prions are infectious proteins and over the past few decades, some prions have become renowned for their causative role in several neurodegenerative diseases in animals and humans.
Munn, Alan L +7 more
core +1 more source
Corrigendum: Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis. [PDF]
McAlary L +3 more
europepmc +1 more source
Genetic Modulators of Prion-Like Protein Propagation in Alzheimer's Disease
Alzheimer's disease (AD) is a widespread neurodegenerative disorder with complex causes. Starting with a historical overview, this paper traces the foundational discoveries by Alois Alzheimer and subsequent research into the roles of Tau, beta-amyloid (Aß), and cellular prion protein (PrPc) in AD progression.
openaire +1 more source
Small critical RNAs in the scrapie agent [PDF]
Unconventional infectious agents cause transmissible spongiform encephalopathy (TSE) diseases including scrapie and bovine spongiform encephalopathy (BSE) in animals and Creutzfeldt-Jakob disease in humans. The protein only hypothesis claims that the TSE
Marie-Madeleine Ruchoux +7 more
core
Scalable assay to identify inhibitors of prion-like propagation of protein misfolding as potential therapeutics for neurodegeneration. [PDF]
Narayan A, Neupane K, Woodside MT.
europepmc +1 more source
Folding and fibril formation of prions [PDF]
Prions diseases are a group of fatal neurodegenerative disorders called the transmissible spongiform encephalopathies (TSEs), which include bovine spongiform encephalopathy in cattle, scrapie in sheep and Creutzfeldt-Jakob disease (CJD) in humans ...
Gierusz, Leszek A.
core
Impairment of the Glial Phagolysosomal System Drives Prion-Like Propagation in a <i>Drosophila</i> Model of Huntington's Disease. [PDF]
Davis GH, Zaya A, Pearce MMP.
europepmc +1 more source

