Results 91 to 100 of about 1,227,464 (275)

Smoke and Clouds above the Southeast Atlantic: Upcoming Field Campaigns Probe Absorbing Aerosol’s Impact on Climate [PDF]

open access: bronze, 2016
Paquita Zuidema   +6 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Performance of a five-axis machine tool as a coordinate measuring machine (CMM)

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
The use of machine tools for on-machine coordinate measurement on the workpiece is becoming commonplace. However, numerous errors can adversely affect the measurement accuracy. For instance, the inter-axis parameters are major contributors to the overall
Md Mizanur RAHMAN, Rene MAYER
doaj   +1 more source

PROBING POTENTIAL OUTPUT: MONETARY POLICY, CREDIBILITY AND OPTIMAL LEARNING UNDER UNCERTAINTY [PDF]

open access: yes
The effective conduct of monetary policy is hampered by uncertainty surrounding the level of potential output. Here, the case for following a more aggressive policy to learn about the economy is considered in a model where potential output is changing ...
James Yetman
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Results of Probing for Congenital Nasolacrimal Duct Obstruction in Children Older than 13 Months of Age

open access: yesIndian Journal of Ophthalmology, 2005
PURPOSE: To determine the success rate of probing for congenital nasolacrimal duct obstruction in children older than 13 months of age. METHODS: In a retrospective study of 84 children, 13 months and older who underwent probing for congenital ...
Maheshwari Rajat
doaj  

Clinical features and etiology of retinal vasculitis in Northern Thailand

open access: yesIndian Journal of Ophthalmology, 2013
Purpose: To report on the clinical features and etiology of patients with retinal vasculitis (RV). Materials and Methods: We reviewed medical records of 47 patients (75 affected eyes) diagnosed with RV.
Supanut Apinyawasisuk   +3 more
doaj   +1 more source

Probing nonstandard decoherence effects with solar and KamLAND neutrinos [PDF]

open access: green, 2007
G. L. Fogli   +4 more
openalex   +1 more source

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