Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
ASSISTING STUDENTS TO ATTACK WRITING TASKS ON IELTS TEST WITH “PROBING TECHNIQUE”
Writing section on IELTS test is commonly considered one of the most difficult parts of test. The test takers can’t even understand what to do with the tasks provided. They eventually write without clearly knowing the expected direction.
Tedi Rohadi
doaj
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Association between salivary alkaline phosphatase levels and periodontal disease: a systematic review and meta-analysis. [PDF]
Alarcón-Sánchez MA +5 more
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Exploring miR-144-3p Expression and its Diagnostic Value in Peri-Implantitis. [PDF]
Yan G, Song H, Lou H.
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Arthroscopically occult meniscotibial instability persists despite systematic transcondylar assessment: Incidence and associated factors during ACL reconstruction. [PDF]
Takahashi T, Matsumoto T.
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Stable valley-like concavity at the midbody of the medial meniscus mimicking meniscocapsular separation: a case report. [PDF]
Hagino T +7 more
europepmc +1 more source

