Results 71 to 80 of about 909,831 (225)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Atomic spin squeezing in an optical cavity
, 2008 We consider squeezing of one component of the collective spin vector of an atomic ensemble inside an optical cavity. The atoms interact with a cavity mode, and the squeezing is obtained by probing the state of the light field that is transmitted through ...
Molmer, Klaus, Nielsen, Anne E. B.
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Indian Journal of Ophthalmology, 2013 Background: The management of Duane retraction syndrome (DRS) is challenging and may become more difficult if an associated accommodative component due to high hyperopia is present. The purpose of this study is to review clinical features and outcomes in
Ramesh Kekunnaya +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Indian Journal of Ophthalmology, 2013 Background: A new emerging complication of trans-scleral fixation of posterior chamber (PC) intraocular lens (IOL) with polypropylene suture is high rates of spontaneous dislocation of the IOL due to disintegration or breakage of suture.
Jagat Ram +3 more
doaj +1 more source
Sensitivity of the LHC to Electroweak Symmetry Breaking: Equivalence Theorem as a Criterion [PDF]
, 1995 Based upon our recent study on the intrinsic connection between the longitudinal weak-boson scatterings and probing the electroweak symmetry breaking (EWSB) mechanism, we reveal the profound physical content of the Equivalence Theorem (ET) as being able ...
He, Hong-Jian +2 more
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Indian Journal of Ophthalmology, 2013 Aim : To establish the frequency, associations and risk factors for age-related macular degeneration (AMD) in hospital population of South India. Materials and Methods : In this cross-sectional hospital based study, 3549 subjects (2090 men and 1459 women)
Bhatiwada Nidhi +4 more
doaj +1 more source
Probing Pseudogap by Josephson Tunneling
, 2000 We propose here an experiment aimed to determine whether there are superconducting pairing fluctuations in the pseudogap regime of the high-$T_c$ materials. In the experimental setup, two samples above $T_c$ are brought into contact at a single point and
A. I. Larkin +12 more
core +1 more source