Clinical effectiveness of procalcitonin- or C-reactive protein-guided antibiotic discontinuation protocols for adult patients who are critically ill with sepsis: a rapid systematic review and meta-analysis. [PDF]
AnaesthesiaSummary Introduction Antibiotics are a first‐line treatment for sepsis, with guidelines recommending a 7‐ to 10‐day course. Prolonged antibiotic use carries significant risks, prompting growing interest in using inflammatory biomarkers, such as procalcitonin or C‐reactive protein, to guide clinical decision‐making on the duration of antibiotic therapy ...
Rafiq S +6 more
europepmc +2 more sources
Biomarkers in respiratory diseases [PDF]
, 2019 The scientific evidence concerning prosthodontic care for the shortened dental arch (SDA) is sparse. This randomized multicenter study aimed to compare two common treatment options: removable partial dental prostheses (RPDPs) for molar replacement vs ...
Dobler, Claudia C
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Early-onset neonatal sepsis: Still room for improvement in procalcitonin diagnostic accuracy studies [PDF]
, 2015 To perform a systematic review assessing accuracy and completeness of diagnostic studies of procalcitonin (PCT) for early-onset neonatal sepsis (EONS) using the Standards for Reporting of Diagnostic Accuracy (STARD) initiative.EONS, diagnosed during the ...
Bonci, Enea +5 more
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Systemic inflammatory response syndrome (SIRS) after extracorporeal membrane oxygenation (ECMO): Incidence, risks and survivals. [PDF]
, 2016 INTRODUCTION: Systemic inflammatory response syndrome (SIRS) is frequently observed after extracorporeal membrane oxygenation (ECMO) decannulation; however, these issues have not been investigated well in the past. METHODS: Retrospective chart review was
Baram, Michael +4 more
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Procalcitonin in Takayasu Arteritis [PDF]
The Journal of Rheumatology, 2014 To the Editor: Procalcitonin (PCT) is an acute-phase protein, a precursor of the hormone calcitonin1. Microbial constituents and proinflammatory mediators such as tumor necrosis factor-α (TNF), interleukin 6 (IL-6), and interferon-γ induce ubiquitous PCT expression during bacterial, parasitic, or fungal infections1,2.
Tombetti, Enrico +8 more
openaire +4 more sources
, 2013 Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely ...
Singer, M
core +1 more source
Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care [PDF]
, 2013 Although many sepsis biomarkers have shown promise in selected patient groups, only C-reactive protein and procalcitonin (PCT) have entered clinical practice.
Berger, Mario +10 more
core +2 more sources
Scientific Reports, 2021 Procalcitonin is a biomarker of systemic inflammation and may have importance in the immune response. The metabolic response to elevated procalcitonin in critical illness is not known.
Hirotada Kobayashi +3 more
doaj +1 more source
Peroxiredoxin 4, a novel circulating biomarker for oxidative stress and the risk of incident cardiovascular disease and all-cause mortality [PDF]
, 2012 BACKGROUND: Oxidative stress has been suggested to play a key role in the development of cardiovascular disease (CVD). The aim of our study was to investigate the associations of serum peroxiredoxin 4 (Prx4), a hydrogen peroxide-degrading peroxidase ...
Abbasi, A. +14 more
core +2 more sources
Serum procalcitonin and C-reactive protein in the evaluation of bacterial infection in generalized pustular psoriasis [PDF]
Anais Brasileiros de DermatologiaBackground There is an obvious need for more prompt and specific biomarkers of bacterial infections in generalized pustular psoriasis patients. Objective The aim of this study was to evaluate the diagnostic properties and define appropriate cut-off ...
Siyu Wang, Zhen Xie, Zhu Shen
doaj +2 more sources