Results 11 to 20 of about 2,971 (153)

Understanding the Role of Estrogen Receptor Status in PRODH/POX-Dependent Apoptosis/Survival in Breast Cancer Cells [PDF]

Biology, 2021
It has been suggested that activation of estrogen receptor α (ER α) stimulates cell proliferation. In contrast, estrogen receptor β (ER β) has anti-proliferative and pro-apoptotic activity.
Ilona Oscilowska, Antonella Forlino, Sylwia Lewoniewska, Jerzy Palka   +3 more
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Proline dehydrogenase (PRODH) gene polymorphisms and the risk of schizophrenia in Iranian populations [PDF]

The Ukrainian Biochemical Journal, 2020
Schizophrenia is a highly heritable mental disorder which can be occurred as a result of mutations or single nucleotide polymorphisms (SNPs) in various genes.
M. Amounajaf, A. Nejadmoghaddam, F. Ghasemvand, Z. H. A. Mehrabani, S. Rahmanzadeh, E. Omidinia, F. H. Moghadam, A. S. Samghabadi   +7 more
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Context of action of Proline Dehydrogenase (ProDH) in the Hypersensitive Response of Arabidopsis [PDF]

BMC Plant Biology, 2014
Background:Proline (Pro) dehydrogenase (ProDH) potentiates the oxidative burst and cell death of the plantHypersensitive Response (HR) by mechanisms not yet elucidated.
Hajirezaei, Mohammad Reza, Monteoliva, Mariela Inés, Rizzi, Yanina, Cecchini, Nicolas Miguel, Alvarez, Maria Elena, Yanina Rizzi, Mohammad-Reza Hajirezaei, Mariela Monteoliva, Nicolás Cecchini, María Alvarez   +9 more
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Detailed analysis of PRODH and PsPRODH reveals no association with schizophrenia

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2003
People with deletion of the chromosome 22q11 region associated with velo cardio-facial syndrome (VCFS) have a remarkably high risk of developing schizophrenia.
N. Williams, N. Norton, H.J. Williams, Norton, N., Williams, Nigel Melville, Spurlock, G., M.J. Owen, M.C. O'Donovan, Kirov, George, Williams, H.J., Zammit, Stanley, G. Spurlock, O'Donovan, Michael Conlon, S. Zammit, G. Kirov, Owen, Michael John   +15 more
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P53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements [PDF]

PLoS ONE, 2013
The tumor suppressor p53 was previously shown to markedly up-regulate the expression of the PRODH gene, encoding the proline dehydrogenase (PRODH) enzyme, which catalyzes the first step in proline degradation.
Monti, P., Yari Ciribilli, Alberto Inga (53320), Alessandra Bisio (218766), Paola Campomenosi, Paola Campomenosi (431559), Paola Monti (218762), POLLEGIONI, LOREDANO, Paola Monti, Loredano Pollegioni, Ivan Raimondi (431557), CAMPOMENOSI, PAOLA, Inga, A., Gilberto Fronza, Yari Ciribilli (218760), Raimondi, I., Fronza, G., Gilberto Fronza (218781), Alessandra Bisio, Bisio, A., Ciribilli, Y., Ivan Raimondi, Alberto Inga, Loredano Pollegioni (431558)   +23 more
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Evidence for association between novel polymorphisms in the PRODH gene and schizophrenia in a Chinese population

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2004
Haploinsufficiency for or mutation in at least one gene from the velocardiofacial syndrome (VCFS) region at chromosome 22q11 is implicated in psychosis.
Liu, X, Murray, RM, Xiehe Liu, Pak C. Sham, Murray, R M, Collier, DA, Xiaohong Ma, Collier, D A, Meng, H, Xueli Sun, Ma, X, Wang, Q, Tao Li, Sham, P C, Qiang Wang, Robin M. Murray, Sham, PC, Xun Hu, Huaqing Meng, Wei Deng, Deng, W, Hu, X, Li, T, Sun, X, David A. Collier   +24 more
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SlgA, the homologue of the human schizophrenia associated PRODH gene, acts in clock neurons to regulate Drosophila aggression [PDF]

Disease Models & Mechanisms, 2017
Mutations in proline dehydrogenase (PRODH) are linked to behavioral alterations in schizophrenia and as part of DiGeorge and velo-cardio-facial syndromes, but the role of PRODH in their etiology remains unclear.
Vulsteke, Veerle, Buhl, Edgar, Veerle Vulsteke, Zwarts, Liesbeth, Liesbeth Zwarts, Edgar Buhl, Hodge, James J.L., Callaerts, Patrick, James J. L. Hodge, Patrick Callaerts, Hodge, James J L   +10 more
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Brief research communication: PRODH gene is associated with executive function in schizophrenic families

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2008
The aim of this study was to investigate the relationship between polymorphisms in the PRODH and COMT genes and selected neurocognitive functions. Six SNPs in PRODH and two SNPs in COMT were genotyped in 167 first-episode schizophrenic families who had ...
Liu, X, Murray, RM, Toulopoulou, T, Xiehe Liu, Wang, Y C, Murray, R M, Collier, DA, Xiaohong Ma, Collier, D A, Meng, H, Ma, X, Ma, X H, Tao Li, Robin M. Murray, Yan, C, Wang, Y, Timothea Toulopoulou, Yingcheng Wang, Meng, H Q, Xun Hu, Huaqing Meng, Yan, C Y, Hu, X, Li, T, Chengying Yan, David A. Collier, Liu, X H   +26 more
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The 22q11 PRODH/DGCR6 deletion is frequent in hyperprolinemic subjects but is not a strong risk factor for ASD. [PDF]

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2016
International audienceThe proline dehydrogenase (PRODH) gene maps to 22q11.2 in the region deleted in the velo-cardio-facial syndrome (VCFS). A moderate to severe reduction (>50%) in PRODH activity resulting from recessive deletions and/or missense ...
Betancur, Catalina, Rovelet-Lecrux, Anne, Afenjar, Alexandra, Delaby, Elsa, Dussardier, Brigitte Gilbert, Scherer, Stephen, W, Richard, Anne-Claire, Campion, Dominique, Thiruvahindrapuram, Bhooma, Eis, Peggy, S, Hatchwell, Eli, Charbonnier, Camille   +11 more
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Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function. [PDF]

PLoS Genetics, 2008
PRODH, encoding proline oxidase (POX), has been associated with schizophrenia through linkage, association, and the 22q11 deletion syndrome (Velo-Cardio-Facial syndrome).
Kristin K. Nicodemus, Lucas Kempf, Venkata A. Mattay, Beth A. Verchinski, Michael F. Egan, Richard E Straub, Daniel R. Weinberger, Daniel R Weinberger, Andreas Meyer-Lindenberg, Joseph H Callicott, Beth A Verchinski, Venkata A Mattay, Richard E. Straub, Kristin K Nicodemus, Radhakrishna Vakkalanka, Michael F Egan, Joseph H. Callicott, Bhaskar Kolachana, Kolachana Bhaskar, Kempf Lucas, Egan Michael F., Weinberger Daniel R., Callicott Joseph H., Verchinski Beth A., Straub Richard E., Mattay Venkata A., Vakkalanka Radhakrishna, Meyer-Lindenberg Andreas, Nicodemus Kristin K.   +28 more
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