Results 31 to 40 of about 2,842 (177)

Association of 757 C/T polymorphismin PRODH gene with Schizophrenia in Iranian population [PDF]

Archives of Advances in Biosciences, 2013
Evidence is emerging for the association of polymorphisms in PRODH gene and increased risk of schizophrenia. In this project, peripheral blood sampling was obtained from 175 schizophrenia patients that their diseases were confirmed by psychiatrists. 185 healthy individuals were considered as control group.
Ghasemvand, Fariba, Rahman zadeh, Saeid, Salehi, Zivar, Fakour, Yousef, Heidari keshel, Saeed, Omidinia, Eskandar   +5 more
openaire   +3 more sources

Constituents of Propolis: Chrysin, Caffeic Acid, p-Coumaric Acid, and Ferulic Acid Induce PRODH/POX-Dependent Apoptosis in Human Tongue Squamous Cell Carcinoma Cell (CAL-27) [PDF]

Frontiers in Pharmacology, 2018
Propolis evokes several therapeutic properties, including anticancer activity. These activities are attributed to the action of polyphenols. Previously it has been demonstrated, that one of the most abundant polyphenolic compounds in ethanolic extracts ...
Katarzyna Celińska-Janowicz, Ilona Zaręba, Urszula Lazarek, Joanna Teul, Michał Tomczyk, Jerzy Pałka, Wojciech Miltyk   +6 more
doaj   +2 more sources

Investigation of genetic association between PRODH gene and schizophrenia in Iranian population [PDF]

Archives of Advances in Biosciences, 2012
Schizophrenia is a complicated, debilitative mental disorder. Evidence is emerging for the association of polymorphisms in PRODH gene and increased risk of schizophrenia. In the present research, we investigated relationship between of this gene and schizophrenia disease by means of a gene polymorphism using PCR-RFLP technique.150 persons suffering ...
Rahman zadeh, Saeid, Shahbaz Mohammadi, Hamid, karimipour, Morteza, Heidari keshel, Saeed   +3 more
openaire   +3 more sources

Disruption of the Prolidase–Proline–PRODH Axis and Oxidative Stress in Schizophrenia

Van Tıp Dergisi
INTRODUCTION: This study aimed to investigate serum levels of proline, prolidase, proline dehydrogenase (PRODH), and reactive oxygen species (ROS) in patients with schizophrenia and healthy controls, to evaluate potential differences between groups and ...
Mehmet Güneş, Burhan Çoban, Betül Uyar, Mehmet Cemal Kaya, Nuriye Mete, Mahmut Bulut   +5 more
doaj   +2 more sources

In Silico Structural Modeling of Wildtype and Mutant PRODH Proteins Involved in Psychiatric Disorder. [PDF]

Proceedings of the National Academy of Sciences, 2021
Abstract Proline dehydrogenase is an important mitochondrial enzyme that is encoded by the PRODH gene. Biologically, a mutation in this gene affects the activity of proline dehydrogenase enzyme that is normally involved in conversion of proline to glutamate.
Muhammad Muzammal, Sumra Wajid Abbasi, Ansar Ahmad Abbasi, Muzammil Ahmad Khan   +3 more
openaire   +4 more sources

PRODH mutations and hyperprolinemia in a subset of schizophrenic patients [PDF]

Human Molecular Genetics, 2002
The increased prevalence of schizophrenia among patients with the 22q11 interstitial deletion associated with DiGeorge syndrome has suggested the existence of a susceptibility gene for schizophrenia within the DiGeorge syndrome chromosomal region (DGCR) on 22q11.
Hélène, Jacquet, Grégory, Raux, Florence, Thibaut, Bernadette, Hecketsweiler, Emmanuelle, Houy, Caroline, Demilly, Sadeq, Haouzir, Gabrielle, Allio, Gael, Fouldrin, Valérie, Drouin, Jacqueline, Bou, Michel, Petit, Dominique, Campion, Thierry, Frébourg   +13 more
openaire   +2 more sources

Δ(1)-pyrroline-5-carboxylate/glutamate biogenesis is required for fungal virulence and sporulation. [PDF]

PLoS ONE, 2013
Proline dehydrogenase (Prodh) and Δ(1)-pyrroline-5-carboxylate dehydrogenase (P5Cdh) are two key enzymes in the cellular biogenesis of glutamate.
Ziting Yao, Chengwu Zou, Hui Zhou, Jinzi Wang, Lidan Lu, Yang Li, Baoshan Chen   +6 more
doaj   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism. [PDF]

Adv Sci (Weinh)
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Ying H, Fan H, Wang Y, Jiang R, Cai D, Cheng H, Wang H, Jiang C, Liang P.   +8 more
europepmc   +2 more sources

Appropriate Activity Assays Are Crucial for the Specific Determination of Proline Dehydrogenase and Pyrroline-5-Carboxylate Reductase Activities

Frontiers in Plant Science, 2020
Accumulation of proline is a widespread plant response to a broad range of environmental stress conditions including salt and osmotic stress. Proline accumulation is achieved mainly by upregulation of proline biosynthesis in the cytosol and by inhibition
Sandrine Lebreton, Cécile Cabassa-Hourton, Arnould Savouré, Dietmar Funck, Giuseppe Forlani   +4 more
doaj   +1 more source

Arabidopsis Proline Dehydrogenase Contributes to Flagellin-Mediated PAMP-Triggered Immunity by Affecting RBOHD

Molecular Plant-Microbe Interactions, 2016
Plants activate different defense systems to counteract the attack of microbial pathogens. Among them, the recognition of conserved microbial- or pathogen-associated molecular patterns (MAMPs or PAMPs) by pattern-recognition receptors stimulates MAMP- or
Georgina Fabro, Yanina Soledad Rizzi, María Elena Alvarez   +2 more
doaj   +1 more source