Results 51 to 60 of about 2,971 (153)
Physiologia Plantarum, Volume 178, Issue 3, May/June 2026.ABSTRACT Plants are frequently exposed to adverse conditions. Priming, also known as acclimation or hardening, induces stress memory and prepares plants for future challenges by activating defense and protective mechanisms. For this reason, priming is an effective means to maintain plant yield in the face of climate change. Memory behind the priming is
Aslihan Temel, Nihal Gören‐Sağlam
wiley +1 more source
Diagram of the PRODH gene, representing the variants investigated in this study and their locations.
, 2014 Diagram of the PRODH gene, representing the variants investigated in this study and their locations.
Karen M. Yamada (519133) +16 more
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Investigation of genetic association between PRODH gene and schizophrenia in Iranian population
Archives of Advances in Biosciences, 2012 Schizophrenia is a complicated, debilitative mental disorder. Evidence is emerging for the association of polymorphisms in PRODH gene and increased risk of schizophrenia. In the present research, we investigated relationship between of this gene and schizophrenia disease by means of a gene polymorphism using PCR-RFLP technique.150 persons suffering ...
Rahman zadeh, Saeid +3 more
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The severe form of type I hyperprolinaemia results from homozygous inactivation of the PRODH gene [PDF]
Journal of Medical Genetics, 2003 Since the original reports of hyperprolinaemia by Scriver et al 1 and Shafer et al ,2 two types of this rare metabolic disorder have been biochemically characterised3: type I (MIM 239500) results from the defect of the enzyme proline dehydrogenase (oxidase), which ensures the conversion of proline into Δ-1-pyrroline-5-carboxylate (P5C), the first step ...
H, Jacquet +8 more
openaire +2 more sources
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
Advanced Science, Volume 13, Issue 19, 2 April 2026.The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 4, April 2026.A hepatic‐differentiated subpopulation is associated with lymphovascular invasion in clear cell renal cell carcinoma. A visual summary of the key findings from our multi‐omics analysis. The TITANIA framework enabled the identification of a hepatic‐differentiated ccRCC subpopulation characterized by the upregulation of liver‐like metabolic pathways and ...
Shugo Yajima +12 more
wiley +1 more source
GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer
Advanced Science, Volume 13, Issue 13, 3 March 2026.Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello +10 more
wiley +1 more source
Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle +6 more
wiley +1 more source
Intracellular Prodh activity of C. parasitica strains in various culture mediaa.
, 2013 aProdh activity was expressed as 1 μM of P5C formed per min per 100 mg of mycelium. The data are from three replicates.
Hui Zhou (13228) +6 more
core +1 more source
How copy number variations shape brain developmental disorders: Unraveling the synaptic puzzle
Psychiatry and Clinical Neurosciences, Volume 80, Issue 3, Page 166-179, March 2026.Neurodevelopmental disorders (NDDs), such as schizophrenia (SCZ), Attention‐deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), learning disabilities, and intellectual disabilities (ID), are highly prevalent. One significant genetic factor associated with NDDs is copy number variations (CNVs), which are structural changes in the ...
Tianqi Wang +3 more
wiley +1 more source