Results 71 to 80 of about 2,971 (153)

PRODH rs450046 and proline x COMT Val(158)Met interaction effects on intelligence and startle in adults with 22q11 deletion syndrome

open access: yes, 2015
22q11 deletion syndrome (22q11DS) is associated with an increased risk for psychotic disorders, suggesting a relationship between genotypes and the pathophysiology of psychotic disorders.
Bloemen, Oswald J. N.   +6 more
core   +1 more source

Riboflavin-responsive hyperprolinemia type I with a PRODH p.Thr466Met variant: Clinical and fibroblast-based evidence

open access: yesMolecular Genetics and Metabolism
Hyperprolinemia type I (HP1) is a rare autosomal recessive disorder caused by biallelic variants in PRODH, encoding the FAD-dependent enzyme proline dehydrogenase. Although persistent hyperprolinemia has been associated with neurodevelopmental and neuropsychiatric manifestations, no established effective treatment is available.
Jun, Kido   +5 more
openaire   +2 more sources

Electrochemical behavior of dye-linked L-proline dehydrogenase on glassy carbon electrodes modified by multi-walled carbon nanotubes

open access: yes, 2010
A glassy carbon electrode (GC) was modified by multi-walled carbon nanotubes (MWCNTs). The modified electrode showed a pair of redox peaks that resulted from the oxygen-containing functional groups on the nanotube surface.
Yosuke Okezaki   +7 more
core   +1 more source

Proteomic and functional analysis of proline dehydrogenase 1 link proline catabolism to mitochondrial electron transport in Arabidopsis thaliana

open access: yes, 2016
International audienceProline accumulates in many plant species in response to environmental stresses. Upon relief from stress, proline is rapidly oxidized in mitochondria by proline dehydrogenase (ProDH) and then by pyrroline-5-carboxylate dehydrogenase
Guivarc'H, Anne   +16 more
core   +1 more source

Effetto di PRODH e ROS nella tumorigenesi e progressione del cancro del polmone

open access: yes
Il cancro al polmone è la principale causa di morte per tumore in tutto il mondo. Per migliorare i risultati terapeutici è necessario comprendere più a fondo i meccanismi molecolari alla base della sua patogenesi.
BERNO, ELENA
core  

Functional complementation of a Saccharomyces cerevisiaeΔ-PUT1 yeast strain with the TcPRODH ORF (1.7 Kb).

open access: yes, 2013
(A) The yeast strains Δ-PUT1, Δ-PUT1 transformed with either empty vector (Δ-PUT1/pYES) or vector carrying the PRODH gene (Δ-PUT/PRODH) were grown in culture medium containing a mix of amino acids with the exception of proline (SD-URA Gal) or ...
Brian Suárez Mantilla (435600)   +8 more
core   +1 more source

Unravelling the role of proline dehydrogenase (PRODH) in lung adenocarcinoma: implications for cellular senescence and the tumor microenvironment

open access: yes
Proline dehydrogenase (PRODH) is a mitochondrial flavoenzyme that catalyzes proline oxidation. The electrons generated from this reaction can be used to produce ATP or ROS, potentially affecting several cellular processes, such as survival, apoptosis ...
Raffaella Cinquetti   +5 more
core  

A Lysine to Alanine Mutant in Escherichia coli PutA Remarkably Reduces Its PRODH Activity

open access: yes, 2018
The imino acid proline plays a critical function in the oxidative stress response in organisms. The catabolism of proline is catalyzed by two enzymes PRODH and P5CDH, which constitute a single protein known as PutA in gram-negative bacteria.
Thelen, Brandon
core  

Mitonuclear discordance modulates mitochondrial ageing dynamics in natural <i>Drosophila</i> populations. [PDF]

open access: yesProc Natl Acad Sci U S A
Bettinazzi S   +4 more
europepmc   +1 more source

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