Results 61 to 70 of about 4,962 (199)
Structural Basis for the Substrate Inhibition of Proline Utilization A by Proline
Molecules, 2017 Proline utilization A (PutA) is a bifunctional flavoenzyme that catalyzes the two-step oxidation of l-proline to l-glutamate using spatially separated proline dehydrogenase (PRODH) and l-glutamate-γ-semialdehyde dehydrogenase (GSALDH) active sites ...
David A. Korasick +4 more
doaj +1 more source
Physiologia Plantarum, Volume 178, Issue 3, May/June 2026.ABSTRACT Plants are frequently exposed to adverse conditions. Priming, also known as acclimation or hardening, induces stress memory and prepares plants for future challenges by activating defense and protective mechanisms. For this reason, priming is an effective means to maintain plant yield in the face of climate change. Memory behind the priming is
Aslihan Temel, Nihal Gören‐Sağlam
wiley +1 more source
Expression, purification and initial characterization of Halobacterium proline dehydrogenase [PDF]
, 2005 only availableNature recycles proline by converting it to glutamate. This 4-electron oxidation process is catalyzed by two catabolic enzymes, proline dehydrogenase (PRODH) and Δ1-pyrroline-5-carboxylate dehydrogenase (P5CDH). Inborn defects in PRODH and
Tanner, Jack, West, Jeremy
core
Association of 757 C/T polymorphismin PRODH gene with Schizophrenia in Iranian population
Archives of Advances in Biosciences, 2013 Evidence is emerging for the association of polymorphisms in PRODH gene and increased risk of schizophrenia. In this project, peripheral blood sampling was obtained from 175 schizophrenia patients that their diseases were confirmed by psychiatrists. 185 healthy individuals were considered as control group.
Ghasemvand, Fariba +5 more
openaire +1 more source
Non-redundant functions of two proline dehydrogenase isoforms in Arabidopsis
BMC Plant Biology, 2010 Background Proline (Pro) accumulation is a widespread response of prokaryotic and eukaryotic cells subjected to osmotic stress or dehydration. When the cells are released from stress, Pro is degraded to glutamate by Pro-dehydrogenase (ProDH) and ...
Müller Gudrun +2 more
doaj +1 more source
GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer
Advanced Science, Volume 13, Issue 13, 3 March 2026.Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello +10 more
wiley +1 more source
Osmolytes: Proline metabolism in plants as sensors of abiotic stress [PDF]
, 2017 Proline accumulation occurs in a large range of plant species in retaliation to the numerous abiotic stresses. An exclusive research pattern suggests there is a pragmatic relation between proline accumulation and plant stress tolerance.
Sengar, R. S. +2 more
core +2 more sources
Iranian Journal of Microbiology, 2011 Background and Objectives: Proline dehydrogenase (ProDH; 1.5.99.8) plays an important role in specific determination of plasma proline level in biosensor and diagnostic kits.
H Shahbaz- Mohammadi, E Omidinia
doaj
Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle +6 more
wiley +1 more source
Translational Oncology, 2023 Background: Lung cancer is a serious threat to human life. It is of great significance to elucidate the pathogenesis of lung cancer and search for new markers.
Lihong Zhang +6 more
doaj +1 more source