Results 161 to 170 of about 3,816 (187)

Baricitinib and Lonafarnib Synergistically Target Progerin and Inflammation, Improving Lifespan and Health in Progeria Mice. [PDF]

Int J Mol Sci
Krüger P, Schroll M, Fenzl FQ, Hartinger R, Lederer EM, Görlach A, Gordon LB, Cavalcante P, Iacomino N, Rathkolb B, Pimentel JAA, Östereicher M, Spielmann N, Wolf CM, de Angelis MH, Djabali K.   +15 more
europepmc   +1 more source

Old enough to be a model? On the role of maturity in stem cell-based models for neuropsychiatric disorders. [PDF]

Neurosci Appl
He B, Smedler E.
europepmc   +1 more source

Impact of miR-181a on SIRT1 Expression and Senescence in Hutchinson-Gilford Progeria Syndrome. [PDF]

Diseases
Lederer EM, Fenzl FQ, Krüger P, Schroll M, Hartinger R, Djabali K.   +5 more
europepmc   +1 more source

Single-cell RNA sequencing analysis reveals the critical role of fibroblasts in aortic progeria-associated vascular remodeling in Hutchinson-Gilford progeria syndrome mice. [PDF]

Front Immunol
Sun Q, Yang L, Zhou Z, Wu N, Li C, Hu Q, Cong X.   +6 more
europepmc   +1 more source

Analysis of Beta-Dystroglycan in Different Cell Models of Senescence. [PDF]

Int J Mol Sci
Jimenez-Gutierrez GE, Zavaleta-Vásquez TI, Lizcano-Meneses JA, Garcia-Aguirre IA, Laredo-Cisneros MS, Magaña JJ, Winder SJ, Cordero-Martínez J, Cisneros B.   +8 more
europepmc   +1 more source

RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria. [PDF]

Mol Cell
Behera AK, Kim JJ, Kordale S, Pekovic F, Damodaran AP, Kumari B, Vidak S, Dickson E, Xiao MS, Duncan G, Andresson T, Misteli T, Valkov E, Gonatopoulos-Pournatzis T.   +13 more
europepmc   +1 more source

BMI1 represses G-quadruplex DNA formation to maintain genomic stability during replication. [PDF]

J Biol Chem
Hanna R, Deneault E, Bernier G.
europepmc   +1 more source

Disease pathogenicity in Hutchinson-Gilford progeria syndrome mice: insights from lung-associated alterations. [PDF]

Mol Med
Wang J, Guan Y, Wang Y, Tan J, Cao Z, Ding Y, Gao L, Fu H, Chen X, Lin J, Shen N, Fu X, Wang F, Mao J, Hu L.   +14 more
europepmc   +1 more source

The anti-senescence effect of D-β-hydroxybutyrate in Hutchinson-Gilford progeria syndrome involves progerin clearance by the activation of the AMPK-mTOR-autophagy pathway. [PDF]

Geroscience
Monterrubio-Ledezma F, Salcido-Gómez A, Zavaleta-Vásquez T, Navarro-García F, Cisneros B, Massieu L.   +5 more
europepmc   +1 more source

Targeting CRM1 for Progeria Syndrome Therapy. [PDF]

Aging Cell
Soto-Ponce A, De Ita M, Castro-Obregón S, Cortez D, Landesman Y, Magaña JJ, Gonzalo S, Zavaleta T, Soberano-Nieto A, Unzueta J, Arrieta-Cruz I, Nava P, Candelario-Martínez A, García-Aguirre I, Cisneros B.   +14 more
europepmc   +1 more source