Results 171 to 180 of about 3,816 (187)

Mechanistic insights into microRNA-induced neuronal reprogramming of human adult fibroblasts [PDF]

, 2018
Lu, Ya-Lin, Yoo, Andrew S
core   +1 more source

Deregulated miR-145 and miR-27b in Hutchinson-Gilford progeria syndrome: implications for adipogenesis. [PDF]

Aging (Albany NY)
Fenzl FQ, Lederer EM, Brumma L, Krüger P, Schroll M, Wilming F, Djabali K.   +6 more
europepmc   +1 more source

Current potential health benefits of sulforaphane [PDF]

Kim, Jae Kwang, Park, Sang Un
core   +1 more source

Mesenchymal Stem Cell Therapy for Hutchinson-Gilford Progeria: Improvements in Arterial Stiffness and Bone Mineral Density in a Single Case. [PDF]

Children (Basel)
Joo EY, Park JS, Shin HT, Yoo M, Kim SJ, Lee JE, Choi GS.   +6 more
europepmc   +1 more source

Author response: Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria

, 2015
Alexandre Chojnowski, Peh Fern Ong, Esther SM Wong, John SY Lim, Rafidah A Mutalif, Raju Navasankari, Bamaprasad Dutta, Henry Yang, Yi Y Liow, Siu K Sze, Thomas Boudier, Graham D Wright, Alan Colman, Brian Burke, Colin L Stewart, Oliver Dreesen   +15 more
openaire   +1 more source

Author Correction: The syntaxin-binding protein STXBP5 regulates progerin expression. [PDF]

Sci Rep
Qi H, Wu Y, Zhang W, Yu N, Lu X, Liu J.
europepmc   +1 more source

Mechanisms of aging in the cardiovascular system: challenges and opportunities. [PDF]

Front Immunol
Zhao X, Yang X, Lin Y, Lei R, Ding W, He X, Cao Y, Zhang D, Liu P, Liang M, Han Z, Jiang Y.   +11 more
europepmc   +1 more source

Progerin mRNA expression in non-HGPS patients is correlated with widespread shifts in transcript isoforms. [PDF]

NAR Genom Bioinform
Yu R, Xue H, Lin W, Collins FS, Mount SM, Cao K.   +5 more
europepmc   +1 more source

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New insights in Progerin-induced modifications of chromatin landscapes

Biophysical Journal, 2023
Genome structure, expression, and regulation are crucial in maintaining the physiological state of any cell. However, even a single variation in one of these processes can induce genomic instability, leading to different pathologies, including aging and cancer.
Cainero, I, Baldini, F, Usai, C, Bianchini, P, Lanzanò, L, Diaspro, A   +5 more
openaire   +1 more source

Progerin and Its Role in Accelerated and Natural Aging

Molecular Biology, 2022
Well-known theories of aging suggest that a certain metabolic defect negatively affects vital activity of the cell, be it oxidative stress, the accumulation of lesions in DNA, the exhaustion of telomeres, or distorted epigenetic processes. The theory of aging considered in the review postulates that an accumulation of progerin on the inner side of the ...
openaire   +2 more sources