Results 61 to 70 of about 1,264,892 (364)

Identification and verification of the ferroptosis- and pyroptosis-associated prognostic signature for low-grade glioma

Bosnian Journal of Basic Medical Sciences, 2022
Accumulating evidence reveals that ferroptosis and pyroptosis play pivotal roles in tumorigenesis of low-grade glioma (LGG). In this research, we aimed to classify molecular subtypes and further identify and verify a novel multigene signature in LGG on ...
Jie Wang, Jie Ren, JiFeng Liu, Linyun Zhang, Q. Yuan, B. Dong   +5 more
semanticscholar   +1 more source

Construction of a prognostic signature of autophagy-related lncRNAs in non-small-cell lung cancer

BMC Cancer, 2021
Background Autophagy inhibits tumorigenesis by limiting inflammation. LncRNAs regulate gene expression at various levels as RNAs; thus, both autophagy and lncRNAs are closely related to the occurrence and development of tumours.
Xinyang Zhang, Yu Cao, Li Chen
doaj   +1 more source

Comprehensive analysis reveals a metabolic ten-gene signature in hepatocellular carcinoma [PDF]

PeerJ, 2020
Background Due to the complicated molecular and cellular heterogeneity in hepatocellular carcinoma (HCC), the morbidity and mortality still remains high level in the world.
Zhipeng Zhu, Lulu Li, Jiuhua Xu, Weipeng Ye, Borong Chen, Junjie Zeng, Zhengjie Huang   +6 more
doaj   +2 more sources

Development and validation of a hypoxia-stemness-based prognostic signature in pancreatic adenocarcinoma

Frontiers in Pharmacology, 2022
Background: Pancreatic adenocarcinoma (PAAD) is one of the most aggressive and fatal gastrointestinal malignancies with high morbidity and mortality worldwide.
Xiong Tian, Jing Zheng, Wanlan Mou, G. Lu, Shuaishuai Chen, Juping Du, Yufen Zheng, Shiyong Chen, Bo Shen, Jun Li, Na Wang   +10 more
semanticscholar   +1 more source

A robust six-gene prognostic signature for prediction of both disease-free and overall survival in non-small cell lung cancer

Journal of Translational Medicine, 2019
Background The high mortality of patients with non-small cell lung cancer (NSCLC) emphasizes the necessity of identifying a robust and reliable prognostic signature for NSCLC patients.
Shuguang Zuo, Min Wei, Hailin Zhang, Anxian Chen, Junhua Wu, Jiwu Wei, Jie Dong   +6 more
doaj   +1 more source

Development and validation of a novel lipid metabolism-related gene prognostic signature and candidate drugs for patients with bladder cancer

Lipids in Health and Disease, 2021
Background Bladder cancer (BLCA) is a common cancer associated with an unfavorable prognosis. Increasing numbers of studies have demonstrated that lipid metabolism affects the progression and treatment of tumors.
Ke Zhu, Xiaoqiang Liu, Wen Deng, Gongxian Wang, B. Fu   +4 more
semanticscholar   +1 more source

Construction of a four-mRNA prognostic signature with its ceRNA network in CESC

Scientific Reports, 2022
Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) tumorigenesis involves a combination of multiple genetic alteration processes.
Lang Li, Qiusheng Guo, Gaochen Lan, Fei Liu, Wenwu Wang, Xianmei Lv   +5 more
semanticscholar   +1 more source

An individualized immune prognostic signature in lung adenocarcinoma [PDF]

Cancer Cell International, 2020
AbstractBackgroundTumor immune infiltration is closely associated with clinical outcome in lung cancer. We aimed to develop an immune signature to improve the prognostic predictions of lung adenocarcinoma (LUAD).MethodsWe applied “Cell type Identification by Estimating Relative Subsets of RNA Transcripts” method to quantify the fraction of 22 leukocyte
Liangdong Sun, Gening Jiang, Diego Gonzalez-Rivas, Peng Zhang   +3 more
openaire   +3 more sources

Unique metastasis‐associated lncRNA signature optimizes prediction of tumor relapse in lung adenocarcinoma

Thoracic Cancer, 2020
Background Local relapses and metastases are primary causes of death in lung cancer patients. In the present study, we aimed to develop a prognostic signature based on metastasis‐associated lncRNAs in patients with lung adenocarcinoma (LUAD).
Xiaoshi Zhang, Jingyi Han, Lutao Du, Xiaoli Li, Jing Hao, Lili Wang, Guixi Zheng, Weili Duan, Yujiao Xie, Yinghui Zhao, Xin Zhang, Mingjin Zou, Chuanxin Wang   +12 more
doaj   +1 more source

Identification and Validation of a Prognostic Signature for Prostate Cancer Based on Ferroptosis-Related Genes

Frontiers in Oncology, 2021
Ferroptosis, an iron-dependent form of selective cell death, is involved in the development of many cancers. However, ferroptosis related genes (FRGs) in prostate cancer (PCa) are not been well studied.
Huan Liu, Lei Gao, Tiancheng Xie, Jie Li, T. Zhai, Yunfei Xu   +5 more
semanticscholar   +1 more source