A novel small-molecule inhibitor TD6 targets prohibitin 1 (PHB1) and suppresses colorectal cancer pulmonary metastasis by destabilizing mitochondrial complex I. [PDF]
Wang K +18 more
europepmc +1 more source
Cryo-EM structure of the prohibitin complex in open conformation. [PDF]
Hong S +8 more
europepmc +1 more source
Structural basis for prohibitin-mediated regulation of mitochondrial m-AAA protease. [PDF]
Luo D +6 more
europepmc +1 more source
In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment. [PDF]
Rose K +7 more
europepmc +1 more source
Mitochondrial proteins as biomarkers of cellular senescence and age-associated diseases. [PDF]
Panfilova A +7 more
europepmc +1 more source
Development of a Piezoelectric Immunosensor to Rapidly Measure Prohibitin‑1 as a Prognostic Biomarker for Sepsis and Other Serious Infectious Diseases. [PDF]
Kamel ES +4 more
europepmc +1 more source
RNA-based approaches in the diagnosis and treatment of obesity. [PDF]
Parekh K, Sarker G.
europepmc +1 more source
Correction to: Prohibitin 1 inhibits cell proliferation and induces apoptosis <i>via</i> the p53-mediated mitochondrial pathway <i>in vitro</i>. [PDF]
Shi JJ, Dang SS.
europepmc +1 more source
The complexities of respiratory chain biogenesis and maintenance in yeast mitochondria. [PDF]
Carlström A, Vazquez-Calvo C, Ott M.
europepmc +1 more source
Prohibitin 2: At a communications crossroads
AbstractProhibitins (PHBs) are a highly conserved class of proteins first discovered as inhibitors of cellular proliferation. Since then PHBs have been found to have a significant role in transcription, nuclear signaling, mitochondrial structural integrity, cell division, and cellular membrane metabolism, placing these proteins among the key regulators
Irène Faenza +2 more
exaly +4 more sources

