Results 171 to 180 of about 24,430,487 (196)
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Stem Cell Reviews and Reports, 2014
Prohibitins are pleiotropic proteins, whose multiple roles are emerging as key elements in the regulation of cell survival and proliferation. Indeed, prohibitins interact with several intracellular proteins strategically involved in the regulation of cell cycle progression in response to extracellular growth signals.
ROSSI, LEONARDO +6 more
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Prohibitins are pleiotropic proteins, whose multiple roles are emerging as key elements in the regulation of cell survival and proliferation. Indeed, prohibitins interact with several intracellular proteins strategically involved in the regulation of cell cycle progression in response to extracellular growth signals.
ROSSI, LEONARDO +6 more
openaire +3 more sources
Differential binding of prohibitin-2 to estrogen receptor α and to drug-resistant ERα mutants
Biochemical and Biophysical Research Communications, 2015Endocrine resistance is one of the most challenging problems in estrogen receptor alpha (ERα)-positive breast cancer. The transcriptional activity of ERα is controlled by several coregulators, including prohibitin-2 (PHB2). Because of its ability to repress the transcriptional activity of activated ERα, PHB2 is a promising antiproliferative agent.
Takeru Chigira +2 more
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The role of prohibitin-2 in podocytes – mitochondrial function and beyond [PDF]
, 2014 Diseases of the kidney filtration barrier are a major cause of renal failure and cardiovascular mortality. Podocytes maintain the glomerular filtration barrier and podocyte dysfunction leads to the development of glomerulosclerosis, i.e. glomerular scarring.
openaire
Prohibitin-1 and -2 have diverse cell-autonomous effects on inflammatory signaling
The Journal of Immunology, 2018Abstract Prohibitins (PHB1 and PHB2) are proteins that assemble in hetero-oligomeric complexes within the mitochondrial inner membrane and in the plasma membrane lipid rafts where they are at the nexus of metabolic and pro-survival decisions including inflammation.
Christine E Psaltis +7 more
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Prohibitin 2 is a Key Regulator of T Cell Proliferation and Effector Functions
Abstract Prohibitin 2 (PHB2) is a highly conserved protein with essential roles in cell homeostasis and survival across different cell types. Previous studies have shown that the deletion of PHB2 results in an arrest in proliferation due to impaired mitochondrial function regulated by the dynamin-like GTPase OPA1.Johannes F. Vogt +15 more
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Mitochondrial function and morphology in prohibitin 2 deleted ß-cells and hepatocytes
2017Ce projet se concentre sur une famille de protéines mitochondriales: les prohibitines. Les prohibitines (Phb1 et Phb2) sont situées sur la membrane interne des mitochondries et participent à diverses fonctions cellulaires. La délétion in vitro de Phb2 provoque une augmentation du clivage de la machinerie de fusion mitochondriale GTPase OPA1, conduisant
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Prohibitin 2 is associated with WSSV infection by promoting stat translocation
Fish & Shellfish Immunology, 2019Cao Xiao-Tong +2 more
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P.587 Prohibitin 2 study in postmortem prefrontal cortex in schizophrenia
European Neuropsychopharmacology, 2020È. Vila +6 more
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Unveiling the potential of prohibitin in cancer
Cancer Letters, 2015Wen G Jiang, Sarah Koushyar
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