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Prohibitin modulates periodontium differentiation in mice development

Frontiers in Cell and Developmental Biology
Introduction: Prohibitin (PHB) is an essential scaffold protein that modulates signaling pathways controlling cell survival, metabolism, inflammation, and bone formation. However, its specific role in periodontium development remains less understood. This study aims to elucidate the expression pattern and function of PHB in periodontium development and
Yam Prasad Aryal +17 more
openaire +3 more sources

Functional characterization of prohibitins by conditional inactivation in the mouse [PDF]

, 2008
Prohibitins comprise an evolutionary conserved and ubiquitously expressed family of membrane proteins implicated in a large variety of cellular processes. Large assemblies of PHB1 and PHB2 subunits are localized in the inner membrane of mitochondria, but
Merkwirth, Carsten
core

Mammalian m-AAA Proteases as Key Regulators of Mitochondrial Function - Analysis of Dominant Negative Mutant Variants [PDF]

, 2009
To ensure the removal of excess and non-assembled proteins, mitochondria require a protein quality control system which is constituted by several proteases located in different compartments of mitochondria.
Raschke, Ines
core

Mitochondrial chaperones in cancer: from molecular biology to clinical diagnostics [PDF]