Results 141 to 150 of about 267,372 (195)

Evidence for Proline Catabolic Enzymes in the Metabolism of Thiazolidine Carboxylates

Thiazolidine carboxylates such as thiazolidine-4-carboxylate (T4C) and thiazolidine-2-carboxylate (T2C) are naturally occurring sulfur analogues of proline. These compounds have been observed to have both beneficial and toxic effects in cells. Given that
John J. Tanner (1333191), Yizi Mao (11669872), Thomas G. Smith (9040705), Javier Seravalli (1264638), Donald F. Becker (742832), Martha Morton (566328)   +5 more
core   +1 more source

Gastric Cancer: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, Diagnosis, and Management

MedComm, Volume 7, Issue 11, November 2026.
This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin, Xingya Wang, Yangtao Wu, Qian Liu, Qian Ren, Hui Wang, Jingbo Zhai   +6 more
wiley   +1 more source

Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta

Plant, Cell &Environment, Volume 49, Issue 11, Page 8306-8321, November 2026.
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng, Kevin Frausto, Sarah Haesaerts, Taylor J. Meyer, Maruša Prolič‐Kalinšek, Seán E. O'Leary, Remy Loris, Paul B. Larsen   +7 more
wiley   +1 more source

Proline catabolism in liver

, 2009
The goal of this work was to localize one of the enzymes involved in proline oxidation, ∆¹-pyrroline-5-carboxylate dehydrogenase (P5CDh) and to gain an understanding of the factors affecting proline catabolism in rat liver.
Haslett, Michael Roland
core   +1 more source

Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to targeted cancer therapy. [PDF]

Mol Cell Biochem, 2020
Huynh TYL, Zareba I, Baszanowska W, Lewoniewska S, Palka J.   +4 more
europepmc   +1 more source

Rhizobial Symbiosis Enhances Salinity Tolerance in Legumes Through Coordinated Physiological and Molecular Responses: Evidence From Common Vetch and Pea

Plant, Cell &Environment, Volume 49, Issue 11, Page 8912-8931, November 2026.
ABSTRACT Soil salinisation severely constrains crop production. Legumes rely on rhizobial symbiosis for sustainable nitrogen acquisition. Although salinity is known to impair nodulation and nitrogen fixation, how symbiosis influences plant tolerance to salt stress remains unclear.
María Isabel López‐Román, Lucía Zurita, Cristina Castaño‐Herrero, Lucía De la Rosa, Elena Ramírez‐Parra   +4 more
wiley   +1 more source

Proline dehydrogenase, a rate-limiting catabolic enzyme, affecting the growth and pathogenicity of Toxoplasma gondii tachyzoites by regulating the proline metabolism and mitochondrial function of the parasite. [PDF]

Parasit Vectors
Geng XL, Li JY, Xu HY, Wu JP, Tao DL, Chen JM, Fan YY, Yang X, Song JK, Zhao GH.   +9 more
europepmc   +1 more source

Noncovalent Inhibition and Covalent Inactivation of Proline Dehydrogenase by Analogs of <i>N</i>-Propargylglycine. [PDF]

Biochemistry
Tanner JJ, Ji J, Bogner AN, Scott GK, Patel SM, Seravalli J, Gates KS, Benz CC, Becker DF.   +8 more
europepmc   +1 more source

The transport and catabolism of L-proline by cowpea Rhizobium NGR 234

, 1991
Cowpea Rhizobium NGR234 grows with a mean generation time of 3.5 h on L-proline; intracellular catabolism via proline oxidase and pyrroline 5-carboxylate dehydrogenase is induced by proline.
Holliday, S., Glenn, A.R., Dilworth, M.J.   +2 more
core  

Biochemical, structural, and cellular characterization of S-but-3-yn-2-ylglycine as a mechanism-based covalent inactivator of the flavoenzyme proline dehydrogenase. [PDF]

Arch Biochem Biophys
Meeks KR, Ji J, Scott GK, Campbell AC, Nix JC, Tadeo A, Ellerby LM, Benz CC, Tanner JJ.   +8 more
europepmc   +1 more source