Results 161 to 170 of about 46,423 (228)

Curcumin‐Loaded GelMA Microspheres Alleviate Osteoarthritis: Transcriptomic Evidence for Immune Microenvironment Remodeling and ECM Homeostasis Restoration

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
This study provides the first multi‐model evidence combined with transcriptomic validation, demonstrating that Cur‐MS not only directly protects chondrocytes and restores extracellular matrix homeostasis but also modulates the joint inflammatory immune microenvironment.
Bin Jiang, Xin Jiang, Shaobo Li, Hao Niu, Wenbin Ji   +4 more
wiley   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, Volume 293, Issue 15, Page 4554-4577, August 2026.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha, Holly M. Weisfelder, Thanh D. Do   +2 more
wiley   +1 more source

Context of action of proline dehydrogenase (ProDH) in the Hypersensitive Response of Arabidopsis. [PDF]

BMC Plant Biol, 2014
Monteoliva MI, Rizzi YS, Cecchini NM, Hajirezaei MR, Alvarez ME.   +4 more
europepmc   +1 more source

Decoding stress resilience in soybean: Regulatory networks and precision breeding under climate change

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2838-2868, August 2026.
This review covers recent progress in the understanding of stress‐responsive regulatory networks in soybean and highlights emerging genomic and breeding strategies. Integrating molecular insights and precision breeding will help to accelerate the development of climate‐resilient soybean cultivars.
Ali Shahzad, Monan Sun, Shuangkang Pei, Xiaoyu Liu, Yinhe Zhang, Keheng Xu, Hongtao Gao, Yonggang Zhou, Haiyan Li   +8 more
wiley   +1 more source

Melatonin seed priming: A climate‐smart, green strategy to enhance abiotic stress tolerance in plants

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2942-2975, August 2026.
This review synthesizes how melatonin seed priming preconditions seeds to enhance tolerance against diverse abiotic stresses. It highlights the underlying mechanisms and proposes an integrative roadmap of advanced molecular and breeding tools to design next‐generation, stress‐smart plants.
Ali Raza, Yiran Li, Chunli Guo, Erna Karalija, Evgenios Agathokleous, Meng Jiang, Jie Zhou, Vasileios Fotopoulos, Zhangli Hu   +8 more
wiley   +1 more source

Climate change and crop resilience: harnessing metabolomics for predicting stress tolerance

New Phytologist, Volume 251, Issue 3, Page 975-995, August 2026.
Summarised methodology for metabolite biomarker discovery and genomic targets selection for those metabolites to predict high‐throughput phenotypic and agronomic traits of interest for direct uptake in breeding programmes. Summary Global warming is driving climate change to levels not experienced since the advent of agriculture, primarily due to ...
Agyeya Pratap, Arash Fazeli, Ali Bandehagh, Nicolas L. Taylor   +3 more
wiley   +1 more source

Kinetic and isotopic characterization of L-proline dehydrogenase from Mycobacterium tuberculosis. [PDF]

Biochemistry, 2013
Serrano H, Blanchard JS.
europepmc   +1 more source

Ectopic Expression of ScALDH21 From a Desert Moss Enhances Cotton Resistance to Verticillium Wilt via the Modulation of Jasmonates and Phenylpropanoid Pathways

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4916-4932, August 2026.
ABSTRACT Biotic stresses, particularly Verticillium wilt (VW), lead to a global decline in cotton yields. Here, we demonstrate that ectopic expression of ScALDH21, a gene from the desiccation‐tolerant moss Syntrichia caninervis Mitt. and absent in angiosperms, enhances cotton's resistance to VW.
Honglan Yang, Xiaoshuang Li, Tohir A. Bozorov, Jianwei Zhang, Aerguli Jiamahate, Dawei Zhang, Jiancheng Wang, Qilin Yang, Zongrang Liu, Dina Mahesati, Haijiang Xu, Shuangxia Jin, Daoyuan Zhang, Yongqiang Dai   +13 more
wiley   +1 more source

Proline dehydrogenase regulates redox state and respiratory metabolism in Trypanosoma cruzi. [PDF]

PLoS One, 2013
Paes LS, Suárez Mantilla B, Zimbres FM, Pral EM, Diogo de Melo P, Tahara EB, Kowaltowski AJ, Elias MC, Silber AM.   +8 more
europepmc   +1 more source