Results 161 to 170 of about 47,460 (254)

An N‐acetyltransferase‐MAPK fusion protein modulates developmental reprogramming in Physcomitrium patens

New Phytologist, Volume 251, Issue 1, Page 321-339, July 2026.
Summary We discovered a previously uncharacterized moss‐specific protein, Rosetta NATD‐MAPK 1 (RAK1) in Physcomitrium patens, which uniquely integrates MAP kinase (MAPK)‐dependent signaling with N‐acetyltransferase activity. Through phenotypical and biochemical analyses, we characterized RAK1 function in the regulation of the 2D‐to‐3D growth transition.
Cloe de Luxán‐Hernández, Thomas J. Ammitsøe, Jakob V. Kanne, Sabrina Stanimirovic, Rocío Redondo‐Rodríguez, Milena E. Roux, Liechi Zhang, Zoe Weeks, Michael Schutzbier, Gerhard Dürnberger, Elisabeth Roitinger, Oliver Spadiut, Masaki Ishikawa, Mitsuyasu Hasebe, Laura A. Moody, Yasin F. Dagdas, Eleazar Rodriguez, Morten Petersen   +17 more
wiley   +1 more source

Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to targeted cancer therapy. [PDF]

Mol Cell Biochem, 2020
Huynh TYL, Zareba I, Baszanowska W, Lewoniewska S, Palka J.   +4 more
europepmc   +1 more source

Enhancing Tolerance to Combined Heat and Drought Stress in Cool‐Season Grain Legumes: Mechanisms, Genetic Insights, and Future Directions

Plant, Cell &Environment, Volume 49, Issue 7, Page 3848-3870, July 2026.
ABSTRACT The increasing frequency of concurrent heat and drought stress poses a significant challenge to agricultural productivity, particularly for cool‐season grain legumes, including broad bean (Vicia Faba L.), lupin (Lupinus spp.), lentil (Lens culinaris Medik), chickpea (Cicer arietinum L.), grasspea (Lathyrus sativus L.), pea (Pisum sativum L ...
Manu Priya, Muhammad Farooq, Kadambot H. M. Siddique   +2 more
wiley   +1 more source

Soybean Inositol Polyphosphate 5‐Phosphatase 8 Confers Salt Tolerance by Reducing Sodium Influx Through Inositol 1,4,5‐Trisphosphate Signalling

Plant, Cell &Environment, Volume 49, Issue 7, Page 4420-4434, July 2026.
ABSTRACT Evidence suggests that the metabolism of inositol and its derivatives may be involved in various biological processes including salt tolerance, but there has been limited understanding. Ectopic expression of Gs5PTase8, an inositol polyphosphate 5‐phosphatase cloned from wild soybean (Glycine soja), significantly enhanced salt tolerance in ...
Qi Jia, Yuan Chen, Defeng Kong, Hanyu Fan, Song Sun, Yuhang Liu, Jiahui Fu, Man‐Wah Li, Fuk‐Ling Wong, Qinghua Li, Kangjing Liang, Hon‐Ming Lam, Wen‐Xiong Lin   +12 more
wiley   +1 more source

Proline dehydrogenase, a rate-limiting catabolic enzyme, affecting the growth and pathogenicity of Toxoplasma gondii tachyzoites by regulating the proline metabolism and mitochondrial function of the parasite. [PDF]

Parasit Vectors
Geng XL, Li JY, Xu HY, Wu JP, Tao DL, Chen JM, Fan YY, Yang X, Song JK, Zhao GH.   +9 more
europepmc   +1 more source

Noncovalent Inhibition and Covalent Inactivation of Proline Dehydrogenase by Analogs of <i>N</i>-Propargylglycine. [PDF]

Biochemistry
Tanner JJ, Ji J, Bogner AN, Scott GK, Patel SM, Seravalli J, Gates KS, Benz CC, Becker DF.   +8 more
europepmc   +1 more source

A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Protein kinases (PKs) are enzymes that catalyze phosphorylation of protein substrates involved in a wide variety of biological signalling pathways. This review describes the different families and mechanisms of action and regulation of protein kinases, together with the different classes of fluorescent biosensors that have been engineered and ...
Timothe Abbura, May C. Morris
wiley   +1 more source

Biochemical, structural, and cellular characterization of S-but-3-yn-2-ylglycine as a mechanism-based covalent inactivator of the flavoenzyme proline dehydrogenase. [PDF]

Arch Biochem Biophys
Meeks KR, Ji J, Scott GK, Campbell AC, Nix JC, Tadeo A, Ellerby LM, Benz CC, Tanner JJ.   +8 more
europepmc   +1 more source

Regulation of proline utilization in Salmonella typhimurium: Autogenous regulation by a membrane-associated dehydrogenase

, 1993
Salmonella typhimurium and Escherichia coli can utilize proline as a sole carbon or nitrogen source. Proline utilization requires the expression of the two genes in the put operon: the putP gene, which encodes proline permease, and the putA gene, which ...
Ostrovsky de Spicer, Paula Cristina
core  

Semi‐Rational Engineering of Formate Dehydrogenase Reveals Loop Dynamics as a Key Determinant of Thermostability

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Semi‐rational engineering yields a thermostable Bacillus simplex formate dehydrogenase variant (Q125F) with a 25‐fold longer half‐life at 60°C and strong resistance to chemo‐inactivation. Molecular dynamics reveal enhanced π–π interactions stabilizing a flexible loop and enabling efficient NADH regeneration for robust biocatalytic detoxification ...
Rattima Boonkumkrong, Sahachat Soithongcharoen, Pitchayathida Mee‐udorn, Paweenapon Chunthaboon, Somchart Maenpuen, Thanyada Rungrotmongkol, Pratchaya Watthaisong, Ruchanok Tinikul   +7 more
wiley   +1 more source