Results 171 to 180 of about 46,423 (228)

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

Plant, Cell &Environment, Volume 49, Issue 8, Page 5849-5865, August 2026.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz, Łukasz Marczak, Aleksander Strugała, Maria Tomys, Ewelina Ratajczak, Tomasz Skrzypczak, Przemysław Wojtaszek, Anna Kasprowicz‐Maluśki, Agnieszka Szuba   +8 more
wiley   +1 more source

Plug-and-play - enzymatic amino acid production from methanol and carbon dioxide. [PDF]

Nat Commun
Willers VP, Lehmann V, Müller S, Vogelgsang F, Roth A, Blombach B, Pick A, Sieber V.   +7 more
europepmc   +1 more source

Assessment of Antimicrobial Resistance in M. leprae Strains From Kiribati

Tropical Medicine &International Health, Volume 31, Issue 8, Page 1035-1042, August 2026.
ABSTRACT Objectives Kiribati has one of the highest rates of leprosy worldwide. A nationwide screening and chemoprophylaxis program for household leprosy contacts was introduced in 2018. In 2022, population‐wide screening and rifamycin‐based treatment or chemoprophylaxis for leprosy and tuberculosis was introduced as part of the PEARL and COMBINE ...
Patrick O. Campbell, Temea Bauro, Erei Rimon, Nabura Ioteba, Trevor Anderson, Arturo Cunanan, Taulanga Naniseni, Jacqui Gardner, Emma Trowbridge, Nicholas M. Douglas, Stephen T. Chambers   +10 more
wiley   +1 more source

Mechanical Loading Induces Distinct and Shared Responses in Endothelial and Muscle Cells and Reveals Exercise‐Like Molecular Profiles

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Mechanical loading of human endothelial and muscle cells induced several distinct and shared molecular responses, many of which are commonly observed after exercise in vivo. Both cell types secreted acetate and endothelial cells increased serine synthesis from glucose.
Sakari Mäntyselkä, Erik Niemi, Laura Ylä‐Outinen, Kalle Kolari, Liina Uusitalo‐Kylmälä, Alfredo Ortega‐Alonso, Roosa‐Maria Liimatainen, Vasco Fachada, Perttu Permi, Elina Kalenius, Juha J. Hulmi, Riikka Kivelä   +11 more
wiley   +1 more source

"Alternative" or integrated role of mitochondrial glycerol-3-phosphate dehydrogenase. [PDF]

Proc Natl Acad Sci U S A
Lemieux H, Joël Lucien Chevret C, Gnaiger E.   +2 more
europepmc   +1 more source

PGPR Improves Barley Performance Under Saline Irrigation: Agronomic, Biochemical, and Transcriptional Evidence from a Two-Season Field Study. [PDF]

Plants (Basel)
Abdelrady WA, Xu J, Hao L, Li Y, Elshawy EE, Abdel-Azeem AM, El-Wakeel SE, Alagamy HHM, Mostfa EEI, Omara AE, Eryan NL, Aboulila AA, Zhao C, Zeng F.   +13 more
europepmc   +1 more source

Exogenous γ-aminobutyric acid promotes 2-acetyl-1-pyrroline biosynthesis by enriching glutamate and optimizing its metabolic flux in pumpkin. [PDF]

Front Plant Sci
Chang J, Zhu X, Ye X, Li J, Chen X, Li J, Zhang B.   +6 more
europepmc   +1 more source

Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria. [PDF]

Biochem J, 2015
Summitt CB, Johnson LC, Jönsson TJ, Parsonage D, Holmes RP, Lowther WT.   +5 more
europepmc   +1 more source

Dysregulated Proline Metabolism Exacerbates Hepatocellular Carcinoma Metastasis via EPRS1-Mediated mRNA Translation. [PDF]

Cancer Commun (Lond)
Zhang H, Gu L, Su X, Chen W, Tan M, Yu H, Zhou H, Gao T, Wang Z, Chen X, Chen W, Chen J, Cheng S.   +12 more
europepmc   +1 more source

Insights into enhanced, divergent, and additive responses to single and combined hypoxia-salt stress. [PDF]

BMC Plant Biol
Jordine A, Alt J, Bonn C, Nolte P, van Dongen JT, Fürtauer L.   +5 more
europepmc   +1 more source