Results 151 to 160 of about 251,378 (256)

A Germline Missense Variant in the NSDHL Gene Underlies Inflammatory Linear Verrucous Epidermal Nevus

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare skin disorder characterized by pruritic, erythematous, and scaly plaques following Blaschko's lines. Known genetic causes include somatic variants in CARD14 and GJA1. In addition, a similar phenotype of congenital hemidysplasia with ichthyosiform nevus and limb defects (CHILD ...
Janan Mohamad   +10 more
wiley   +1 more source

Transcript correlation analysis for the identification of novel plant genes involved in iron metabolism and beyond: what next?

open access: yesPlant Biology, EarlyView.
Transcript correlation analysis allowed the identification of several key nodes in the complex regulatory network of plant iron metabolism. Abstract Arabidopsis thaliana was the first plant genome to be fully sequenced, almost a quarter of a century ago, thanks to The Arabidopsis Genome Initiative, with contributions from scientists worldwide.
I. Murgia, P. Morandini
wiley   +1 more source

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

Post‐exercise ketone supplementation improves endurance performance and mitochondrial adaptations during an 8‐week endurance training intervention

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐eight trained males completed 8 weeks of supervised indoor cycling training, receiving post‐exercise and pre‐sleep ketone monoester (KE, n = 14) or isocaloric placebo (CON, n = 14). Both groups improved 30 min time‐trial performance with training, but KE achieved a 4% higher power output than CON at the end of the training
Ruben Robberechts   +8 more
wiley   +1 more source

Multifactorial Role of Phytogenic CeO2 NPs in Crop Improvement and Stress Alleviation: A Mechanistic Overview

open access: yesPlant-Environment Interactions, Volume 7, Issue 5, October 2026.
The graphical abstract illustrates how CeO2 nanoparticles help plants withstand biotic and abiotic stresses. Their application reduces excessive ROS through enhanced antioxidant defenses, whereas modulating stress signaling, phytohormones, and gene expression.
Faiza Arooj   +6 more
wiley   +1 more source

Application of Omics Technologies for Cowpea Improvement

open access: yesPlant-Environment Interactions, Volume 7, Issue 5, October 2026.
ABSTRACT Cowpea (Vigna unguiculata) is a vital crop for food security, nutrition, and climate resilience in sub‐Saharan African and other semi‐arid regions. However, its improvement is constrained by the complexity of polygenic traits such as drought tolerance, pest resistance, and seed quality.
Junior S. Kamara   +3 more
wiley   +1 more source

ITCH‐Mediated Ubiquitination and Degradation of THBS1: A Key Mechanism for Enhancing Mitochondrial Biogenesis and Alleviating Mouse Skeletal Muscle Atrophy

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim Skeletal muscle atrophy is tightly associated with maladaptive alterations in mitochondrial function and morphology. Itchy E3 ubiquitin‐protein ligase (ITCH) modulates mitochondria, and thrombospondin 1 (THBS1) positively regulates muscle atrophy, but their roles in muscle atrophy are unclear. Methods A muscle atrophy model was established
Wan Yu, Yanteng Wang, Na Li, Difei Wang
wiley   +1 more source

The Crosstalk Between Diabetes and Alzheimer's Disease: A Molecular Perspective

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
Increasing evidence indicates an association between type 2 diabetes mellitus and Alzheimer’s disease, contributing to the proposed concept of AD as “type 3 diabetes.” Shared biological features such as impaired insulin signaling, chronic inflammation, mitochondrial dysfunction, and oxidative stress have been observed in both T2DM and AD.
Deniz Catakli   +3 more
wiley   +1 more source

Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola

open access: yesInsect Molecular Biology, Volume 35, Issue 5, Page 576-593, October 2026.
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez   +1 more
wiley   +1 more source

A factorial multi‐layer analysis reveals non‐additive sulfur–iron interactions shaping metabolic and transcriptional responses in durum wheat

open access: yesNew Phytologist, Volume 252, Issue 1, Page 192-208, October 2026.
Working model of S‐dependent Fe stress integration in durum wheat. S availability acts as the main factor defining the metabolic and transcriptional state of the plant, whereas Fe mainly affects the intensity of these responses. This is particularly evident for OAS, methionine, citrate and asparagine, which accumulated most strongly under combined S ...
Eleonora Coppa   +9 more
wiley   +1 more source

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