Results 101 to 110 of about 11,452 (171)

Structural simplification of the 3‐nitroimidazo[1,2‐a]pyridine antileishmanial pharmacophore: Design, synthesis, and antileishmanial activity of novel 2,4-disubstituted 5-nitroimidazoles

Heterocyclic Communications
As part of our ongoing antileishmanial structure–activity relationship study, a structural simplification of the 3‐nitroimidazo[1,2‐a]pyridine ring to a 5-nitroimidazole moiety was conducted.
Paoli-Lombardo Romain, Primas Nicolas, Hutter Sébastien, Castera-Ducros Caroline, Jacquet Inès, Verhaeghe Pierre, Azas Nadine, Rathelot Pascal, Vanelle Patrice   +8 more
doaj   +1 more source

Characterization of the promastigote surface protease of Leishmania as a membrane-bound zinc endopeptidase

The effects of a variety of inhibitors suggested that the promastigote surface protease (PSP) of Leishmania might be a Zn metalloprotease. To investigate this possibility, at.
Etges, Robert, Bouvier, Jacques, Reichelt, Rudolf, Vogel, Horst, Bordier, Clement   +4 more
core   +1 more source

Meta-1 y Mat-1, proteínas metacíclicas en leishmania: clonación, expresión y caracterización inmunológica

Iatreia, 2000
<p class="MsoNormal"><span style="font-size: 8.5pt; font-family: Arial">Los parásitos del género Leishmania causan un amplio espectro clínico de enfermedades en el hombre, referidos colectivamente como leismaniasis.
Christof Berberich, Robinson Ramírez, Carlos Muskus, Marcel Marín   +3 more
doaj  

Five-layer systems analysis of <i>Leishmania</i> stage differentiation reveals an essential role for protein degradation in parasite development. [PDF]

Elife
Pescher P, Douché T, Giai Gianetto Q, Druart K, Kovářová J, Li B, Cokelaer T, Rajan KS, Piel L, Besse C, Boland A, Deleuze JF, Matondo M, Barrett MP, Michaeli S, Späth GF.   +15 more
europepmc   +1 more source

A Dual-Reporter Fluorescence-Luminescence Assay for Drug Screening in Promastigote and Intracellular Amastigote Stages of <i>Leishmania</i>. [PDF]

Molecules
D'Alessandro S, Parapini S, Calvo-Alvarez E, Perego F, Mazza G, Murugan A, Basilico N.   +6 more
europepmc   +1 more source

Insights into the antibacterial, antifungal, and antiparasitic activities of functionalized ZnO quantum dots. [PDF]

Sci Rep
Ashiq S, Mustafa G.
europepmc   +1 more source

Peptides as a Therapeutic Alternative Against Leishmaniasis: A Scoping Review. [PDF]

Chem Biol Drug Des
da Veiga Oliveira ME, Dyminski Parente Ribeiro E, Guenther OHP, Tomiotto-Pellissier F.   +3 more
europepmc   +1 more source

Regulation of Leishmania surface coat proteins by the nuclear protein ESB1. [PDF]

J Cell Sci
Arias Del Angel JA, Dobramysl U, Davidson L, Wheeler RJ, Sunter JD.   +4 more
europepmc   +1 more source

Targeting <i>Leishmania</i> Fe-SOD and Glucose Metabolism with Tripodal and Pyridinacyclophane Polyamines as a Chemotherapeutic Strategy. [PDF]

Metabolites
Martín-Montes Á, Delgado-Pinar E, Bonastre I, Clares MP, Verdejo B, Martínez-Camarena Á, Ballesteros-Garrido R, Martín-Escolano R, Rosales-Lombardo MJ, García-España E, Marín C.   +10 more
europepmc   +1 more source

Identification of a conserved gene family with an essential role in <i>Leishmania</i> parasite-insect vector adhesion. [PDF]

Proc Natl Acad Sci U S A
Owino BO, Yanase R, Pruzinova K, Farr H, Lopez Y, Marron AO, Vaughan S, Volf P, Sunter JD.   +8 more
europepmc   +1 more source