Results 91 to 100 of about 11,689 (228)

Compared Antileishmanial Activity of Clomiphene and Tamoxifen

Biomedicines
Drug repositioning is an efficient strategy to search for new treatment alternatives that is especially valuable for neglected parasitic diseases such as leishmaniasis. Tamoxifen and raloxifene are selective estrogen receptor modulators (SERMs) that have
Sergio Sifontes-Rodríguez, Alma Reyna Escalona-Montaño, Ricardo Mondragón Flores, Niurka Mollineda-Diogo, Lianet Monzote Fidalgo, Mónica Edith Mondragón-Castelán, Fedra Alardin-Gutiérrez, Lourdes Araceli López-Enzana, Daniel Andrés Sánchez-Almaraz, Ofelia Pérez-Olvera, María Magdalena Aguirre-García   +10 more
doaj   +1 more source

Study of the stress proteins secreted by Leishmania donovani after treatment with edelfosine, mitelfosine and ilmofosine, and morphological alterations analyzed by electronic microscopy

Parasite, 2009
We studied the stress proteins induced in protozoa Leishmania donovani after treatment with edelfosine, miltefosine and ilmofosine. We studied the morphological and structural modifications caused in the promastigote forms of the parasite after treatment
Azzouz S., Maache M., Sarciron M.E., Petavy A.F., Osuna A.   +4 more
doaj   +1 more source

In vitro promastigote growth profiles of studied L. (L.) donovani isolates.

, 2012
The growth profiles of population A isolates (in black dotted curves) and population B isolates (in full black curves) largely coincide and clearly indicate that all studied isolates had a similar in vitro promastigote growth dynamic.
Hideo Imamura (62469), Sylke Müller (37476), Kirstyn Brunker (181178), Graham H. Coombs (164011), Suman Rijal (181185), Basudha Khanal (181181), Jean-Claude Dujardin (56958), Saskia Decuypere (181176), Manu Vanaerschot (109210)   +8 more
core   +1 more source

The Role of Phosphoglycans in the Susceptibility of Leishmania mexicana to the Temporin Family of Anti-Microbial Peptides

Molecules, 2015
Natural product antimicrobial peptides (AMPs) have been proposed as promising agents against the Leishmania species, insect vector borne protozoan parasites causing the neglected tropical disease leishmaniasis. However, recent studies have shown that the
Gabriela A. Eggimann, Kathryn Sweeney, Hannah L. Bolt, Neshat Rozatian, Steven L. Cobb, Paul W. Denny   +5 more
doaj   +1 more source

Evaluation of Alternative Culture Media for Cost-effective and Reliable in vitro Cultivation of Leishmania

Türkiye Parazitoloji Dergisi
Objective: This study aimed to evaluate the efficiency of commonly available culture media in routine microbiology laboratories for the cultivation of Leishmania tropica (L. tropica) promastigotes.
Yener Özel, İbrahim Çavuş, Gülhan Vardar Ünlü, Mehmet Ünlü, Ahmet Özbilgin   +4 more
doaj   +1 more source

Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds of Dimorphandra gardneriana and Platymiscium floribundum, native plants from Caatinga biome

Pesquisa Veterinária Brasileira, 2012
In recent years, the Brazilian Health Ministry and the World Health Organization have supported research into new technologies that may contribute to the surveillance, new treatments, and control of visceral leishmaniasis within the country.
Nadja S. Vila-Nova, Selene M. Morais, Maria J.C. Falcão, Claudia M.L. Bevilaqua, Fernanda C.M. Rondon, Mary E. Wilson, Icaro G.P. Vieira, Heitor F. Andrade   +7 more
doaj   +1 more source

Simulation cell swimming with different speeds of longitudinal rotation captures the differences in trypomastigote, epimastigote-like and promastigote swimming.

, 2017
(A) Predicted helical path shapes for swimming trypomastigote, epimastigote-like and promastigote cells from measured longitudinal rotation rate, assuming ωκ = 0.6 rad/s.
Richard John Wheeler (487126)
core   +1 more source

PMM resistance selection on intracellular amastigotes: in vitro susceptibility (IC₅₀) of the parent strain and the selected clones as promastigote and as intracellular amastigote to PMM, Sb^III, Sb^V and MIL.

, 2013
Intracellular amastigotes were transformed back to the extracellular (without drug exposure) promastigote stage after each selection cycle. After selection cycle-2, fourteen clones were obtained from the induced PMM-resistant promastigote population.nd ...
Craig D. Shaw (321146), Sarah Hendrickx (321143), Raquel Andrea Inocêncio da Luz (321144), Katharine Carter (321150), Suman Rijal (181185), Louis Maes (191127), Kristel Kuypers (321145), Vasundhra Bhandari (162788), Julien Lonchamp (321147), Shyam Sundar (58354), Paul Cos (233137), Jean-Claude Dujardin (56958), Poonam Salotra (162805)   +12 more
core   +1 more source

Western Blot Analysis of Sera from Leishmania major-Infected BALB/c and C57BL/6 Mice

Journal of Medical Microbiology and Infectious Diseases, 2013
In Leishmania (L.) major-infected BALB/c mice Th2-type cells results in disease progression, whereas C57BL/6-infected mice mount a Th1-type response, which leads to control of the infection.
Sedighe Ebrahimpoor, Saeed Reza Pakzad, Farideh Mohasel Hamedani, Soheila Ajdary   +3 more
doaj  

A study on the cytotoxic effect of cantharidin on Leishmania major promastigote and amastigote survival in vitro

, 2012
Background: Leishmaniasis is one of the major public health problems in many countries. Cantharidin, a type of terpenoid and a potent vesicant found in the Meloidae and Oedemeridae beetle families, has been used to treat wart in traditional medicine ...
Sharifi, Z., Hasan, Z., Maroufi, Y., Ghaffarifar, F., Dalimi, A.   +4 more
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