Results 71 to 80 of about 10,387 (198)
Study of the variables associated with local complement activation in IgA nephropathy
Nefrología (English Edition), 2017 Objectives: 1. To identify the variables that are associated with urinary levels of properdin, MBL, C4d, and C5b-9 in patients with idiopathic IgA nephropathy. 2. To analyse whether urinary levels of MBL and/or C4d are useful for identifying the presence
Alfons Segarra-Medrano +6 more
doaj +1 more source
Biotic and abiotic factors of bactericidal properties variability of ruminant saliva
BIO Web of Conferences, 2020 The microflora of the oral cavity of domestic ruminants, presented by transitive gram-negative species of bacteria (cocci and sticks) in cows, transient and obligate gram-positive (usually cocci) bacteria in sheep was studied. The lowest contamination of
Gilmutdinov Rustam Y. +3 more
doaj +1 more source
Autoantibodies to complement components in C3 glomerulopathy and atypical hemolytic uremic syndrome. [PDF]
, 2014 The alternative pathway of complement is implicated in the pathogenesis of several renal diseases, such as atypical hemolytic uremic syndrome, dense deposit disease and other forms of C3 glomerulopathy.
Józsi, Mihály +6 more
core +1 more source
Host Immune Evasion by Lyme and Relapsing Fever Borreliae: Findings to Lead Future Studies for Borrelia miyamotoi [PDF]
, 2017 The emerging pathogen, Borrelia miyamotoi, is a relapsing fever spirochete vectored by the same species of Ixodes ticks that carry the causative agents of Lyme disease in the US, Europe, and Asia. Symptoms caused by infection with B.
Brandee L. Stone, Catherine A. Brissette
core +1 more source
The Emerging Clinical Usefulness of Complement Measurements [PDF]
, 1977 Not many years ago the main purpose of “complement” seemed to be to drill holes in sheep erythrocytes. In the classic experiment which was part of every medical student’s microbiology laboratory experience, a magic stuff called complement, somewhat ...
Ruddy, Shaun
core +1 more source
Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. [PDF]
, 2018 Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and cancer. While p53 activation is responsible for many features of DBA, the role of immune system is less defined.
Bibikova, Elena +5 more
core +2 more sources
Frontiers in Immunology, 2019 Properdin (FP) is a positive regulator of the immune system stimulating the activity of the proteolytically active C3 convertase C3bBb in the alternative pathway of the complement system. Here we present two crystal structures of FP and two structures of
Dennis V. Pedersen +14 more
doaj +1 more source
Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]
, 2020 Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima +18 more
core
mAbsThe bispecific antibody tarperprumig (ALXN1820) was developed as a treatment option for diseases involving dysregulated complement alternative pathway (AP) activity that could be administered in small volumes, either subcutaneously or intravenously ...
Paul Tamburini +8 more
doaj +1 more source
Some clinical aspects of prolonged clinostatic hypokinesia [PDF]
Attendant problems which arise with prolonged confinement of patients to bed are discussed.
Filatova, L. M. +3 more
core +1 more source