Results 81 to 90 of about 10,182 (218)

S267: PROPERDIN-BLOCKING ANTIBODIES ATTENUATE COMPLEMENT ALTERNATIVE PATHWAY ACTIVATION TRIGGERED BY CELL-FREE HEME IN SICKLE CELL DISEASE MODELS

open access: gold, 2022
Thiago Trovati Maciel   +10 more
openalex   +1 more source

Crystallization and X-ray analysis of monodisperse human properdin.

open access: yesActa Crystallographica Section F Structural Biology Communications, 2019
The 54 kDa protein properdin, also known as factor P (FP), plays a major role in the complement system through the stabilization of the alternative pathway convertases.
D. Pedersen   +3 more
semanticscholar   +1 more source

Molecular characterisation of 10 Dutch properdin type I deficient families: mutation analysis and X-inactivation studies [PDF]

open access: bronze, 2000
R. van den Bogaard   +5 more
openalex   +1 more source

Antibody Inhibition of Properdin Prevents Complement-Mediated Intravascular and Extravascular Hemolysis

open access: yesJournal of Immunology, 2018
Paroxysmal nocturnal hemoglobinuria (PNH) is a serious blood disorder characterized by dysregulated complement activation on blood cells. Eculizumab, the current standard therapy and a humanized anti-C5 mAb, relieves anemia and thrombosis symptoms of PNH
Damodar Gullipalli   +8 more
semanticscholar   +1 more source

Role of properdin in complement-mediated kidney diseases.

open access: yesNephrology, Dialysis and Transplantation, 2018
As part of the innate immune system, the complement system is an important mechanism in our first line of defence, but it can also contribute to the onset of various diseases.
Mieke F. van Essen   +3 more
semanticscholar   +1 more source

ISEV2025 Abstract Book

open access: yes
Journal of Extracellular Vesicles, Volume 14, Issue S1, October 2025.
wiley   +1 more source

properdin

open access: yes
Citation: 'properdin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13612 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

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