Results 151 to 160 of about 3,903,665 (206)
Receptor-mediated Actions of Prorenin in Diabetic Retinopathy
Despite improvements in patient care, the incidence of diabetic retinopathy is dramatically increasing. Recent evidence suggests that a component of a hormonal system, called prorenin, may participate in the development of diabetic organ disease. We will
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Prorenin receptor is needed for podocyte function [PDF]
Nature Reviews Nephrology, 2011 openaire +1 more source
Diabetic retinopathy is the leading cause of blindness in people of working age. The World Health Organization predicts that by 2030 more than 300 million people will have diabetes.
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REVERSIBLE CRYOACTIVATION OF RECOMBINANT HUMAN PRORENIN
, 1992 Cleavage of prorenin's prosegment causes irreversible formation of renin. In contrast, renin activity is reversibly exposed when prorenin is acidified to pH 3.3. Nonetheless, acidification of plasma results in irreversible activation of prorenin, because
J. E. Sealey +3 more
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, 2011 Introduction: The recent discovery of a specific receptor for renin/prorenin (PRR) has added new interest to the potential pharmacological actions of aliskiren, the first direct renin inhibitor.
C.M. Greco +3 more
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Elevated Prorenin Induces Podocyte Injury and Glomerular Fibrosis in cyp1a1-Prorenin Transgenic Rats. [PDF]
Int J Mol SciGu C, Liu X, Wu J, Huang Y.
europepmc +1 more source
Important Role of Renin-Angiotensin System and Vasopressin System in Cardiovascular, Metabolic and Psychogenic Disorders in Pregnancy and Early Postnatal Life: A Narrative Review. [PDF]
Int J Mol SciSzczepańska-Sadowska E.
europepmc +1 more source
Loss of OXGR1 function uncouples intrarenal RAS activation from pendrin and αENaC regulation and blunts angiotensin II-induced hypertension. [PDF]
Front PharmacolCárdenas P +9 more
europepmc +1 more source