Results 111 to 120 of about 3,813 (208)

Protectin DX, a double lipoxygenase product of DHA, inhibits both ROS production in human neutrophils and cyclooxygenase activities. [PDF]

, 2014
International audienceNeutrophils play a major role in inflammation by releasing large amounts of reactive oxygen species (ROS) produced by NADPH oxidase (NOX) and myeloperoxidase (MPO).
Michel Guichardant, Fay, Michèle, Fathi Driss, Boussetta, Tarek, Michel Lagarde, Driss, Fathi, El-Benna, Jamel, Guichardant, Michel, Lagarde, Michel, Tarek Boussetta, Liu, Miao, Michèle Fay, Jamel El‐Benna, Miao Liu, Karama Makni‐Maalej, Makni-Maalej, Karama   +15 more
core   +2 more sources

Protectin DX ameliorates palmitate- or high-fat diet-induced insulin resistance and inflammation through an AMPK-PPARα-dependent pathway in mice

Scientific Reports, 2017
Protectin DX (PDX), a double lipoxygenase derivative of docosahexaenoic acid, has been reported to attenuate inflammation and insulin resistance. In the current study, we explored the effects of PDX on hyperlipidemia-induced insulin resistance and ...
Tae Woo Jung, Hyoung-Chun Kim, A. M. Abd El-Aty, Ji Hoon Jeong   +3 more
doaj   +1 more source

protectin

Citation: 'protectin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13614 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Protectin DX attenuates LPS-induced inflammation and insulin resistance in adipocytes via AMPK-mediated suppression of the NF-κB pathway [PDF]

, 2018
Several studies have demonstrated that protectins, ω-3 fatty acid-derived proresolution mediators, may ameliorate inflammation. Recently, protectin DX (PDX) was also reported to attenuate inflammation and insulin resistance in several cell types ...
Ji Hoon Jeong, Kim, Hyoung-Chun, Hyoung-Chun Kim, Tae Woo Jung, Chung, Yoon Hee, Yoon Hee Chung, Abd El-Aty, A. M., Jeong, Ji Hoon, A. M. Abd El-Aty, Jung, Tae Woo   +9 more
core   +1 more source

Therapeutic Applicability of Anti-Inflammatory and Proresolving Polyunsaturated Fatty Acid-Derived Lipid Mediators

The Scientific World Journal, 2010
The enzymatic oxygenation of polyunsaturated fatty acids by lipoxygenases and cyclo-oxygenases is a resourceful mode of formation of specific autacoids that regulate the extent and pace of the inflammatory response. Arachidonate-derived eicosanoids, such
Gerard L. Bannenberg
doaj   +1 more source

Structure, distribution, and functional role of protectin (CD59) in complement-susceptibility and in immunotherapy of human malignancies - (Review) [PDF]

, 1998
Protectin (CD59) is a glycosyl-phosphatidylinositol-anchored cell membrane glycoprotein, ubiquitously expressed, though to a different extent, on benign and malignant cells.
Sigalotti L, Altomonte M, Fonsatti E, Gasparollo A, Visintin A, Maio M, Coral S, Lamaj E, Brasoveanu LI   +8 more
core  

Integrated hydrogel system targeting AMPK/PPARγ signaling in osteoarthritis immunometabolic regulation

Journal of Nanobiotechnology
This study introduces CA@PDX HMs, an injectable sustained-release hydrogel system for osteoarthritis (OA) therapy designed to regulate the immunometabolic microenvironment via the AMPK/PPARγ signaling pathway.
Lifeng Ding, Xiufei Teng, Wei Du, Yonghao Zhang, Baozhe Liu, Shang Piao   +5 more
doaj   +1 more source

Roles of Protectin D1 (PD1) and Protectin Conjugate for Tissue Regeneration 1 (PCTR1) During Respiratory Syncytial Virus Infection [PDF]

A27. VIRAL INFECTIONS: IMMUNITY AND BASIC MECHANISMS, 2020
K. Walker, N. Krishnamoorthy, T.R. Brüggeman, P.C. Norris, C.N. Serhan, B.D. Levy   +5 more
openaire   +1 more source

Protectin D1 (PD1) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Protectin DX (PDX) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source