Beyond cartilage degeneration: osteoarthritis as a systems failure of inflammation regulation. [PDF]
Bar-Or D +4 more
europepmc +1 more source
A synergistic multimodality treatment approach to address the key drivers of wound chronicity. [PDF]
Lohr JM +6 more
europepmc +1 more source
Immunomodulatory Effects of Omega-3 Fatty Acids: Mechanistic Insights and Health Implications. [PDF]
Bodur M +3 more
europepmc +1 more source
The Potential of Bioactive Plant Phytochemicals, Pro-Resolving Anti-Inflammatory Lipids, and Statins in the Inhibition of Intervertebral Disc Degeneration, Low Back Pain Resolution, Disc Functional Repair, and Promotion of Intervertebral Disc Regeneration. [PDF]
Melrose J.
europepmc +1 more source
Attenuation of adipose tissue inflammation by pro-resolving lipid mediators.
Clark M, Suur BE, Soták M, Börgeson E.
europepmc +1 more source
The biosynthetic pathways of the protectins
Evidence for the biosynthetic pathways of the specialized pro-resolving mediator (SPM) protectin D1 (PD1) and its biochemical further local metabolism were presented during the 8th European Workshop on Lipid Mediators, organized June 29th-July 1st, 2022, in Stockholm, Sweden. Herein, we provide an extended and detailed discussion of these topics.
Trond Vidar Hansen
exaly +3 more sources
Protectins: Their biosynthesis, metabolism and structure-functions
Several lipoxygenase enzymes and cyclooxygenase-2 stereoselectively convert the polyunsaturated fatty acids arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid, and n-3 docosapentaenoic acid into numerous oxygenated products. Biosynthetic pathway studies have shown, during the resolution phase of acute inflammation, that distinct families of ...
Trond Vidar Hansen, Charles N Serhan
exaly +5 more sources
Resolvins and Protectins in Inflammation Resolution [PDF]
The critical role of inflammatory processes in health and disease has long been recognized,1 yet the detailed molecular mechanisms and biological events that regulate the progression and resolution of inflammation remain of interest. A number of recent investigations have provided strong evidence that the resolution of inflammation is not a passive ...
Nicos Petasis, Charles N Serhan
exaly +3 more sources

