Frontiers in Pharmacology, 2019 A western type diet and lifestyle play an important role in the development of chronic diseases, yet little insight into the precise cellular and biomolecular mechanisms has emerged. It is known that an unbalanced diet may result in obesity and diabetes.
Trond Vidar Hansen +2 more
doaj +1 more source
Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22 [PDF]
, 2018 Resolution-phase macrophage population orchestrates active dampening of the inflammation by secreting anti-inflammatory and proresolving products including interleukin (IL)-10 and lipid mediators (LMs).
Holopainen, Minna +8 more
core +2 more sources
Can endogenous lipid molecules serve as predictors and prognostic markers of coronary heart disease?
Lipids in Health and Disease, 2008 Dyslipidemia, and inflammatory markers: high-sensitivity C-reactive protein (hs-CRP), myeloperoxidase (MPO), lipoprotein associated phospholipase A2(Lp-PLA2), and lipid peroxides (LP) are insufficient to predict the onset, extent, and prognosis of CHD ...
Das Undurti N
doaj +1 more source
Neuroinflammation is a putative target for the prevention and treatment of perioperative neurocognitive disorders. [PDF]
, 2019 IntroductionThe demographics of aging of the surgical population has increased the risk for perioperative neurocognitive disorders in which trauma-induced neuroinflammation plays a pivotal role.Sources of dataAfter determining the scope of the review ...
Lai, IK, Li, R, Maze, M, Saxena, S
core +2 more sources
Resolvin E1 and protectin D1 activate inflammation-resolution programmes [PDF]
Nature, 2007 Resolution of acute inflammation is an active process essential for appropriate host responses, tissue protection and the return to homeostasis. During resolution, specific omega-3 polyunsaturated fatty-acid-derived mediators are generated within resolving exudates, including resolvin E1 (RvE1) and protectin D1 (PD1).
Jan M, Schwab +3 more
openaire +2 more sources
Ageing: Is there a role for arachidonic acid and other bioactive lipids? A review
Journal of Advanced Research, 2018 Ageing is inevitable. Recent studies suggest that it could be delayed. Low-grade systemic inflammation is seen in type 2 diabetes mellitus, hypertension and endothelial dysfunction that are common with increasing age.
Undurti N. Das
doaj +1 more source
Frontiers in Immunology, 2021 Viral pneumonias are a major cause of morbidity and mortality, owing in part to dysregulated excessive lung inflammation, and therapies to modulate host responses to viral lung injury are urgently needed.
Katherine H. Walker +5 more
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N-3 fatty acids as resolvents of inflammation in the A549 cells [PDF]
, 2015 Background Fatty acids and their derivatives are one of the most crucial inflammation mediators. The aim of our study was to evaluate the impact of polyunsaturated fatty acids as eicosanoids precursors on the A549 cell line.
Czepiel, Jacek +8 more
core +1 more source
Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver. Role for omega-3 epoxides [PDF]
, 2018 Soluble epoxide hydrolase (sEH) is an emerging therapeutic target in a number of diseases that have inflammation as a common underlying cause. sEH limits tissue levels of cytochrome P450 (CYP) epoxides derived from omega-6 and omega-3 polyunsaturated ...
Alcaraz-Quiles, José +9 more
core +1 more source
Role of omega-3 fatty acids and their metabolites in asthma and allergic diseases
Allergology International, 2015 Omega-3 fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are found naturally in fish oil and are commonly thought to be anti-inflammatory nutrients, with protective effects in inflammatory diseases including asthma and allergies ...
Jun Miyata, Makoto Arita
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