Results 21 to 30 of about 4,926 (194)
Biomedicines, 2022 Introduction: Polycystic ovary syndrome (PCOS) is an endocrinological disorder that affects 5–15% of women of their reproductive age and is a frequent cause of infertility. Major symptoms include hyperandrogenism, ovulatory dysfunction, and often obesity
Pedro-Antonio Regidor +6 more
doaj +2 more sources
Can essential fatty acids reduce the burden of disease(s)? [PDF]
Lipids in Health and Disease, 2008 Coronary heart disease, stroke, diabetes mellitus, hypertension, cancer, depression schizophrenia, Alzheimer's disease, and collagen vascular diseases are low-grade systemic inflammatory conditions that are a severe burden on health care resources ...
Das Undurti N
doaj +2 more sources
Can vagus nerve stimulation halt or ameliorate rheumatoid arthritis and lupus? [PDF]
Lipids in Health and Disease, 2011 Acetylcholine, the principal vagus neurotransmitter, inhibits inflammation by suppressing the production of pro-inflammatory cytokines through a mechanism dependent on the α7 nicotinic acetylcholine receptor subunit (alpha7nAChR) that explains why vagus ...
Das Undurti N
doaj +2 more sources
Journal of Infection in Developing Countries, 2017 Introduction: The severity of urinary tract infection (UTI) produced by uropathogenic Escherichia coli (UPEC) is due to the expression of a wide spectrum of virulence genes. E.
Yandag Munkhdelger +4 more
doaj +3 more sources
Molecular Circuits of Resolution in Airway Inflammation [PDF]
The Scientific World Journal, 2010 Inflammatory diseases of the lung are common, cause significant morbidity, and can be refractory to therapy. Airway responses to injury, noxious stimuli, or microbes lead to leukocyte recruitment for host defense.
Troy Carlo, Bruce D. Levy
doaj +2 more sources
Pharmacological effects of specialized pro-resolving mediators in sepsis-induced organ dysfunction: a narrative review [PDF]
Frontiers in ImmunologySepsis is a life-threatening syndrome of organ dysfunction, characterized by uncontrolled inflammatory response and immune dysregulation, often leading to multiple organ failure and even death.
Shujun Sun +22 more
doaj +2 more sources
Molecules, 2022 Specialized pro-resolving mediators (SPMs) are lipid mediators derived from poly-unsaturated fatty acids (PUFAs) which have been demonstrated to have an important role in the inflammation environment, preventing an overreaction of the organism and ...
Mariarosaria Valente +4 more
doaj +1 more source
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Omega-3 DHA as a blank canvas: A molecular approximation to how lipid mediators modulate LGR6 in inflammation resolution. [PDF]
Protein SciAbstract The leucine‐rich repeat‐containing G protein‐coupled receptor 6 (LGR6) has a potential role in inflammation resolution and different cancer processes. In this study, we employed computational techniques, including molecular docking and molecular dynamics simulations of mammalian membrane‐embeded systems, to understand the activation mechanism ...
Pérez-Sánchez Á +3 more
europepmc +2 more sources
Bioactive lipid-based therapeutic approach to COVID-19 and other similar infections
Archives of Medical Science, 2021 COVID-19 is caused by SARS-CoV-2 infection. Epithelial and T, NK, and other immunocytes release bioactive lipids especially arachidonic acid (AA) in response to microbial infections to inactivate them and upregulate the immune system.
Undurti N. Das
doaj +1 more source