Results 21 to 30 of about 5,197 (155)

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Major structure-activity relationships of resolvins, protectins, maresins and their analogues

open access: yes, 2023
Resolvins, protectins and maresins are a series of polyunsaturated fatty acid-derived molecules which play important roles in the resolution of inflammation.
O'Sullivan, Killian   +2 more
core   +1 more source

Resolution of inflammation: Therapeutic potential of pro-resolving lipids in Type 2 diabetes mellitus and associated renal complications

open access: yesFrontiers in Immunology, 2012
The role of inflammation in the pathogenesis of type 2 diabetes mellitus (T2DM) and its associated complications is increasingly recognized. The resolution of inflammation is actively regulated by endogenously produced lipid mediators such as lipoxins ...
Emma eBorgeson, Catherine eGodson
doaj   +1 more source

Endogenous inhibitory mechanisms in asthma

open access: yesJournal of Allergy and Clinical Immunology: Global, 2023
Endogenous inhibitory mechanisms promote resolution of inflammation, enhance tissue repair and integrity, and promote homeostasis in the lung. These mechanisms include steroid hormones, regulatory T cells, IL-10, prostaglandin E2, prostaglandin I2 ...
Sergio E. Chiarella, MD   +1 more
doaj   +1 more source

Synthesis, Structural Confirmation, and Biosynthesis of 22-OH-PD1n-3 DPA

open access: yesMolecules, 2019
PD1n-3 DPA belongs to the protectin family of specialized pro-resolving lipid mediators. The protectins are endogenously formed mediators that display potent anti-inflammatory properties and pro-resolving bioactivities and have attracted interest in drug
Jannicke Irina Nesman   +5 more
doaj   +1 more source

Differential Mobility Separation of Leukotrienes and Protectins

open access: yes, 2015
Differential mobility spectrometry (DMS) is capable of separating stereoisomeric molecular ions based on their mobility in an oscillating electrical field with an asymmetric waveform.
Cyrus Papan (1598611)   +7 more
core   +2 more sources

Short-term n-3 fatty acid supplementation but not aspirin increases plasma proresolving mediators of inflammation[S]

open access: yesJournal of Lipid Research, 2014
Resolution of inflammation is an active process involving specialized proresolving mediators (SPM) formed from the n-3 fatty acids. This study examined the effect of n-3 fatty acid supplementation and aspirin on plasma SPMs in healthy humans.
Anne Barden   +4 more
doaj   +1 more source

Métabolisme oxygéné des acides gras polyinsaturés et fonction dans les cellules sanguines et vasculaires1

open access: yesOléagineux, Corps gras, Lipides, 2011
Most polyunsaturated fatty acids have the minimal 1,4-cis,cis-pentadiene configuration to be oxygenated into a conjugated diene hydroperoxide. This product is usually reduced into the corresponding hydroxy derivative by cell glutathione peroxidases.
Lagarde Michel
doaj   +1 more source

Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

open access: yesJournal of Lipid Research, 2013
Placental inflammation is associated with several pregnancy disorders. Inflammation is limited by anti-inflammatory and proresolving mechanisms, the latter partly mediated by resolvins and protectins derived from omega-3 polyunsaturated fatty acids (n ...
Megan L. Jones   +6 more
doaj   +1 more source

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